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TMEM86B transmembrane protein 86B [ Homo sapiens (human) ]

Gene ID: 255043, updated on 7-Jun-2020

Summary

Official Symbol
TMEM86Bprovided by HGNC
Official Full Name
transmembrane protein 86Bprovided by HGNC
Primary source
HGNC:HGNC:28448
See related
Ensembl:ENSG00000180089 MIM:617806
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in gall bladder (RPKM 7.8), duodenum (RPKM 5.4) and 24 other tissues See more
Orthologs

Genomic context

See TMEM86B in Genome Data Viewer
Location:
19q13.42
Exon count:
3
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (55226638..55228763, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (55738002..55740632, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene synaptotagmin 5 Neighboring gene protein tyrosine phosphatase receptor type H Neighboring gene protein phosphatase 6 regulatory subunit 1 Neighboring gene microRNA 6804 Neighboring gene microRNA 6802

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC30208

Gene Ontology Provided by GOA

Function Evidence Code Pubs
alkenylglycerophosphocholine hydrolase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
alkenylglycerophosphocholine hydrolase activity IDA
Inferred from Direct Assay
more info
PubMed 
alkenylglycerophosphoethanolamine hydrolase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
alkenylglycerophosphoethanolamine hydrolase activity IDA
Inferred from Direct Assay
more info
PubMed 
ether hydrolase activity TAS
Traceable Author Statement
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
ether lipid metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
phosphatidylcholine acyl-chain remodeling TAS
Traceable Author Statement
more info
 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
endoplasmic reticulum membrane TAS
Traceable Author Statement
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
lysoplasmalogenase
Names
alkenylglycerophosphocholine hydrolase
alkenylglycerophosphoethanolamine hydrolase
NP_001358942.1
NP_776165.3

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001372013.1NP_001358942.1  lysoplasmalogenase isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC010327, BC033193, BX448118, CV029437
    Related
    ENST00000589190.1
  2. NM_173804.5NP_776165.3  lysoplasmalogenase isoform 1

    See identical proteins and their annotated locations for NP_776165.3

    Status: VALIDATED

    Source sequence(s)
    AC010327, BC023000, BC033193, BX448118, CV029437
    Consensus CDS
    CCDS12920.1
    UniProtKB/Swiss-Prot
    Q8N661
    Related
    ENSP00000321038.3, ENST00000327042.5
    Conserved Domains (1) summary
    pfam07947
    Location:47217
    YhhN; YhhN-like protein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    55226638..55228763 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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