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sds22 protein phosphatase regulatory subunit Sds22 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2543597, updated on 15-Mar-2024

Summary

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Gene symbol
sds22
Gene description
protein phosphatase regulatory subunit Sds22
Locus tag
SPAC4A8.12c
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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Location:
chromosome: I
Exon count:
2
Sequence:
Chromosome: I; NC_003424.3 (2573160..2574641, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene putative lipase Neighboring gene miscRNA Neighboring gene fatty acid synthase alpha subunit Lsd1 Neighboring gene 20S proteasome component beta 5 Neighboring gene putative ribose-phosphate pyrophosphokinase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mitotic regulation of protein phosphatases by the fission yeast sds22 protein. Stone EM, et al. Curr Biol, 1993 Jan. PMID 15335873
  2. S. pombe gene sds22+ essential for a midmitotic transition encodes a leucine-rich repeat protein that positively modulates protein phosphatase-1. Ohkura H, et al. Cell, 1991 Jan 11. PMID 1846086
  3. A PP1-PP2A phosphatase relay controls mitotic progression. Grallert A, et al. Nature, 2015 Jan 1. PMID 25487150, Free PMC Article
  4. CPF-associated phosphatase activity opposes condensin-mediated chromosome condensation. Vanoosthuyse V, et al. PLoS Genet, 2014 Jun. PMID 24945319, Free PMC Article
  5. Dsc E3 ligase localization to the Golgi requires the ATPase Cdc48 and cofactor Ufd1 for activation of sterol regulatory element-binding protein in fission yeast. Burr R, et al. J Biol Chem, 2017 Sep 29. PMID 28821619, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein phosphatase activator activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
enables protein phosphatase regulator activity IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of mitotic metaphase/anaphase transition IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of mitotic sister chromatid separation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in signaling NAS
Non-traceable Author Statement
more info
  
Component Evidence Code Pubs
part_of PTW/PP1 phosphatase complex IPI
Inferred from Physical Interaction
more info
 PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytosol HDA PubMed 
is_active_in nucleus HDA PubMed 
is_active_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
protein phosphatase regulatory subunit Sds22

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    2573160..2574641 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019253.2 → NP_593824.1  protein phosphatase regulatory subunit Sds22 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593824.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P22194
    Conserved Domains (4) summary
    smart00446
    Location:302 → 320
    LRRcap; occurring C-terminal to leucine-rich repeats
    sd00033
    Location:84 → 105
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:104 → 146
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:217 → 271
    LRR_8; Leucine rich repeat
Nucleotide Protein
Heading Accession and Version

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