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dld1 dihydrolipoamide dehydrogenase Dld1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2543269, updated on 19-Nov-2025
Official Symbol
dld1
Official Full Name
dihydrolipoamide dehydrogenase Dld1
Primary source
PomBase:SPAC1002.09c
Locus tag
SPOM_SPAC1002.09C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
dldh
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See dld1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
1
Sequence:
Chromosome: I; NC_003424.3 (1811408..1813740, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene N-acetyltransferase Ats1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene RNA polymerase-specificity factor Mtf1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene snRNP binding protein Sgt1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene GPI-anchor transamidase complex subunit Gaa1

Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. A non-transcriptional role for the glucocorticoid receptor in mediating the cell stress response. Ptushkina M, et al. Sci Rep, 2017 Sep 21. PMID 28935859, Free PMC Article
  2. Chromatin remodeller Fun30(Fft3) induces nucleosome disassembly to facilitate RNA polymerase II elongation. Lee J, et al. Nat Commun, 2017 Feb 20. PMID 28218250, Free PMC Article
  3. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
  4. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article
  5. The genome sequence of Schizosaccharomyces pombe. Wood V, et al. Nature, 2002 Feb 21. PMID 11859360

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables dihydrolipoyl dehydrogenase (NADH) activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables dihydrolipoyl dehydrogenase (NADH) activity IEA
Inferred from Electronic Annotation
more info
  
enables dihydrolipoyl dehydrogenase (NADH) activity ISO
Inferred from Sequence Orthology
more info
  
enables flavin adenine dinucleotide binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in 2-oxoglutarate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in pyruvate decarboxylation to acetyl-CoA ISO
Inferred from Sequence Orthology
more info
  
involved_in pyruvate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of glycine cleavage complex ISO
Inferred from Sequence Orthology
more info
  
is_active_in mitochondrial matrix IC
Inferred by Curator
more info
  
located_in mitochondrial matrix IEA
Inferred from Electronic Annotation
more info
  
is_active_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of oxoglutarate dehydrogenase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of pyruvate dehydrogenase complex ISO
Inferred from Sequence Orthology
more info
  
Preferred Names
dihydrolipoamide dehydrogenase Dld1

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    1811408..1813740 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001018930.3 → NP_593496.1  dihydrolipoamide dehydrogenase Dld1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593496.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O00087, Q9US50
    Conserved Domains (4) summary
    PRK06327
    Location:45 → 511
    PRK06327; dihydrolipoamide dehydrogenase; Validated
    pfam00070
    Location:219 → 297
    Pyr_redox; Pyridine nucleotide-disulphide oxidoreductase
    pfam02852
    Location:392 → 498
    Pyr_redox_dim; Pyridine nucleotide-disulphide oxidoreductase, dimerization domain
    pfam13450
    Location:50 → 84
    NAD_binding_8; NAD(P)-binding Rossmann-like domain
Nucleotide Protein
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