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rad2 FEN-1 endonuclease Rad2 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2543164, updated on 22-Jun-2024

Summary

Gene symbol
rad2
Gene description
FEN-1 endonuclease Rad2
Locus tag
SPOM_SPAC3G6.06C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
fen1
Old locus tag
SPAC3G6.06c
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Genomic context

See rad2 in Genome Data Viewer
Location:
chromosome: I
Exon count:
3
Sequence:
Chromosome: I; NC_003424.3 (5389586..5391422, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Mpv17/PMP22 family protein 1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene sulfhydryl oxidase

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables 5'-3' DNA exonuclease activity IDA
Inferred from Direct Assay
more info
PubMed 
enables 5'-3' exonuclease activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables 5'-flap endonuclease activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables 5'-flap endonuclease activity IDA
Inferred from Direct Assay
more info
PubMed 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables double-stranded DNA 5'-3' DNA exonuclease activity IDA
Inferred from Direct Assay
more info
PubMed 
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables single-stranded DNA 5'-3' DNA exonuclease activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in DNA replication, removal of RNA primer IEA
Inferred from Electronic Annotation
more info
 
involved_in UV-damage excision repair IDA
Inferred from Direct Assay
more info
PubMed 
involved_in UV-damage excision repair IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in base-excision repair IDA
Inferred from Direct Assay
more info
PubMed 
involved_in mitochondrial DNA metabolic process IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 
is_active_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in site of double-strand break IDA
Inferred from Direct Assay
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    5389586..5391422 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001020403.3NP_594972.1  FEN-1 endonuclease Rad2 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594972.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P39750
    Conserved Domains (3) summary
    cd09907
    Location:222291
    H3TH_FEN1-Euk; H3TH domain of Flap Endonuclease-1, a structure-specific, divalent-metal-ion dependent, 5' nuclease: Eukaryotic homologs
    cd09867
    Location:4345
    PIN_FEN1; PIN domain of Flap Endonuclease-1, a structure-specific, divalent-metal-ion dependent, 5' nuclease and homologs
    PTZ00217
    Location:1379
    PTZ00217; flap endonuclease-1; Provisional