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paa1 protein phosphatase regulatory subunit Paa1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2543042, updated on 13-Mar-2024

Summary

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Gene symbol
paa1
Gene description
protein phosphatase regulatory subunit Paa1
Locus tag
SPAP8A3.09c
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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Location:
chromosome: I
Exon count:
7
Sequence:
Chromosome: I; NC_003424.3 (5330096..5333012, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene putative phospho-2-dehydro-3-deoxyheptonate aldolase Neighboring gene miscRNA Neighboring gene miscRNA Neighboring gene miscRNA Neighboring gene myosin II light chain cdc4 Neighboring gene putative protein sorting protein Neighboring gene putative GTPase Mtg2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The regulatory subunits of fission yeast protein phosphatase 2A (PP2A) affect cell morphogenesis, cell wall synthesis and cytokinesis. Kinoshita K, et al. Genes Cells, 1996 Jan. PMID 9078365
  2. Regulation of fission yeast morphogenesis by PP2A activator pta2. Bernal M, et al. PLoS One, 2012. PMID 22403715, Free PMC Article
  3. A PP1-PP2A phosphatase relay controls mitotic progression. Grallert A, et al. Nature, 2015 Jan 1. PMID 25487150, Free PMC Article
  4. Shugoshin collaborates with protein phosphatase 2A to protect cohesin. Kitajima TS, et al. Nature, 2006 May 4. PMID 16541025
  5. Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I. Riedel CG, et al. Nature, 2006 May 4. PMID 16541024

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein phosphatase regulator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein phosphatase regulator activity NAS
Non-traceable Author Statement
more info
  
Process Evidence Code Pubs
involved_in asymmetric protein localization to old mitotic spindle pole body IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in establishment or maintenance of cytoskeleton polarity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in meiotic centromeric cohesion protection in anaphase I EXP
Inferred from Experiment
more info
 PubMed 
involved_in meiotic centromeric cohesion protection in anaphase I IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of septation initiation signaling IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein dephosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of FAR/SIN/STRIPAK complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in chromosome, centromeric region IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytosol HDA PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in mitotic actomyosin contractile ring IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in mitotic spindle pole body EXP
Inferred from Experiment
more info
 PubMed 
is_active_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of protein phosphatase type 2A complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of protein phosphatase type 2A complex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
protein phosphatase regulatory subunit Paa1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    5330096..5333012 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001020379.2 → NP_594948.1  protein phosphatase regulatory subunit Paa1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594948.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q10293, Q9UT08
    Conserved Domains (3) summary
    cd00020
    Location:447 → 545
    ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
    pfam13646
    Location:486 → 586
    HEAT_2; HEAT repeats
    sd00044
    Location:285 → 313
    HEAT; HEAT repeat [structural motif]
Nucleotide Protein
Heading Accession and Version

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