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sck1 serine/threonine protein kinase S6K family Sck1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542492, updated on 15-Apr-2026
Official Symbol
sck1
Official Full Name
serine/threonine protein kinase S6K family Sck1
Primary source
PomBase:SPAC1B9.02c
Locus tag
SPOM_SPAC1B9.02C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Try the new Transcripts and proteins table
See sck1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
4
Sequence:
Chromosome: I; NC_003424.3 (2402016..2404703, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene GATOR2-SEACAT complex WD repeat subunit Seh1 Neighboring gene ncRNA Neighboring gene nuclear import protein Nxt2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ribosome biogenesis protein

Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. The cyclic AMP/PKA signal pathway is required for initiation of spore germination in Schizosaccharomyces pombe. Hatanaka M, et al. Yeast, 2001 Feb. PMID 11180454
  2. Protein kinase Sck1 is involved in trehalase activation by glucose and nitrogen source in the fission yeast Schizosaccharomyces pombe. Soto T, et al. Microbiology (Reading), 1997 Jul. PMID 9245826
  3. Phosphorylation-dependent tuning of mRNA deadenylation rates. Stowell JAW, et al. Nat Struct Mol Biol, 2026 Jan. PMID 41184513, Free PMC Article
  4. A new Schizosaccharomyces pombe chronological lifespan assay reveals that caloric restriction promotes efficient cell cycle exit and extends longevity. Chen BR, et al. Exp Gerontol, 2009 Aug. PMID 19409973, Free PMC Article
  5. S. pombe sck2+, a second homologue of S. cerevisiae SCH9 in fission yeast, encodes a putative protein kinase closely related to PKA in function. Fujita M, et al. Curr Genet, 1998 Apr. PMID 9560431

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Sck1 negatively regulates PKA activity via binding to Gpa2.
    Title: Sck1 negatively regulates Gpa2-mediated glucose signaling in Schizosaccharomyces pombe.
Submit: New GeneRIF Correction
Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables lipid binding ISM
Inferred from Sequence Model
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity EXP
Inferred from Experiment
more info
 PubMed 
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in TORC1 signaling IEA
Inferred from Electronic Annotation
more info
  
involved_in TORC1 signaling IPI
Inferred from Physical Interaction
more info
 PubMed 
involved_in intracellular signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in intracellular signal transduction IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in negative regulation of adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in negative regulation of conjugation with cellular fusion IEA
Inferred from Electronic Annotation
more info
  
involved_in negative regulation of conjugation with cellular fusion IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytosol HDA PubMed 
Preferred Names
serine/threonine protein kinase S6K family Sck1

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    2402016..2404703 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019184.3 → NP_593754.1  serine/threonine protein kinase S6K family Sck1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593754.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P50530, Q9UTF3
    Conserved Domains (3) summary
    smart00220
    Location:302 → 563
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd05586
    Location:308 → 633
    STKc_Sck1_like; Catalytic domain of Suppressor of loss of cAMP-dependent protein kinase-like Serine/Threonine Kinases
    cl14603
    Location:139 → 294
    C2; C2 domain
Nucleotide Protein
Heading Accession and Version

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