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CXorf58 chromosome X open reading frame 58 [ Homo sapiens (human) ]

Gene ID: 254158, updated on 10-Dec-2024

Summary

Official Symbol
CXorf58provided by HGNC
Official Full Name
chromosome X open reading frame 58provided by HGNC
Primary source
HGNC:HGNC:26356
See related
Ensembl:ENSG00000165182 AllianceGenome:HGNC:26356
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Biased expression in testis (RPKM 2.2) and thyroid (RPKM 0.1) See more
Orthologs
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Genomic context

See CXorf58 in Genome Data Viewer
Location:
Xp22.11
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (23907932..23939509)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (23491609..23523191)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (23926123..23957626)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene BRD4-independent group 4 enhancer GRCh37_chrX:23800811-23802010 Neighboring gene uncharacterized LOC127933115 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chrX:23825194-23826393 Neighboring gene spermidine/spermine N1-acetyltransferase 1 Neighboring gene ribosomal protein L9 pseudogene 7 Neighboring gene apolipoprotein O Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chrX:23900936-23901702 Neighboring gene ReSE screen-validated silencer GRCh37_chrX:23905519-23905696 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20707 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29494 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chrX:23970710-23971248 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chrX:23971249-23971786 Neighboring gene Sharpr-MPRA regulatory region 13558 Neighboring gene kelch like family member 15 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29495 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20708 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20709 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20710 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chrX:24043667-24044171 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chrX:24044172-24044675 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:24045883-24046382 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20713 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29496 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29497 Neighboring gene eukaryotic translation initiation factor 2 subunit gamma

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
uncharacterized protein CXorf58

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_016380.1 RefSeqGene

    Range
    5001..36504
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001169574.2NP_001163045.1  uncharacterized protein CXorf58 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1.
    Source sequence(s)
    AC079376, AK058173, BC144007
    UniProtKB/TrEMBL
    B7ZLS7
  2. NM_152761.3NP_689974.2  uncharacterized protein CXorf58 isoform 1

    See identical proteins and their annotated locations for NP_689974.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AC079376, AK058173
    Consensus CDS
    CCDS14209.1
    UniProtKB/Swiss-Prot
    Q96LI9
    UniProtKB/TrEMBL
    B7ZLS7
    Related
    ENSP00000368511.3, ENST00000379211.8

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    23907932..23939509
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011545473.3XP_011543775.1  uncharacterized protein CXorf58 isoform X1

    See identical proteins and their annotated locations for XP_011543775.1

    UniProtKB/Swiss-Prot
    Q96LI9
    UniProtKB/TrEMBL
    B7ZLS7
  2. XM_011545474.3XP_011543776.1  uncharacterized protein CXorf58 isoform X2

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    23491609..23523191
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054326756.1XP_054182731.1  uncharacterized protein CXorf58 isoform X1

    UniProtKB/TrEMBL
    B7ZLS7
  2. XM_054326757.1XP_054182732.1  uncharacterized protein CXorf58 isoform X2