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rad3 ATR checkpoint kinase Rad3 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540719, updated on 12-Aug-2018

Summary

Gene symbol
rad3
Gene description
ATR checkpoint kinase Rad3
Locus tag
SPBC216.05
Gene type
protein coding
RNA name
ATR checkpoint kinase Rad3
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces

Genomic context

See rad3 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003423.3 (903253..913629)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene miscRNA Neighboring gene dynein-anchoring factor Mcp5/Num1 Neighboring gene hypothetical protein Neighboring gene putative methionine sulfoxide Neighboring gene replication fork protection complex subunit Swi1 Neighboring gene phosphatidylinositol kinase Tor2 Neighboring gene protein Cwf11 Neighboring gene miscRNA Neighboring gene putative glutamyl-tRNA amidotransferase alpha subunit

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein serine/threonine kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
protein serine/threonine kinase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Process Evidence Code Pubs
DNA damage checkpoint IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
DNA damage induced protein phosphorylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
DNA repair IMP
Inferred from Mutant Phenotype
more info
PubMed 
histone H2A SQE motif phosphorylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
intra-S DNA damage checkpoint IMP
Inferred from Mutant Phenotype
more info
PubMed 
meiotic recombination checkpoint IMP
Inferred from Mutant Phenotype
more info
PubMed 
mitotic DNA replication checkpoint IMP
Inferred from Mutant Phenotype
more info
PubMed 
mitotic G2 DNA damage checkpoint IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of DNA repair IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of initiation of premeiotic DNA replication IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of mitotic DNA damage checkpoint IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein localization to chromosome, telomeric region IGI
Inferred from Genetic Interaction
more info
PubMed 
telomere maintenance IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
telomere maintenance IGI
Inferred from Genetic Interaction
more info
PubMed 
telomere maintenance IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
chromosome, telomeric region IDA
Inferred from Direct Assay
more info
PubMed 
cytosol HDA PubMed 
nuclear chromatin IDA
Inferred from Direct Assay
more info
PubMed 
nuclear chromosome IDA
Inferred from Direct Assay
more info
PubMed 
nucleolus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
subtelomeric heterochromatin IDA
Inferred from Direct Assay
more info
PubMed 

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    903253..913629
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021264.2NP_595357.1  ATR checkpoint kinase Rad3 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_595357.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q02099
    Conserved Domains (4) summary
    smart00802
    Location:862968
    UME; Domain in UVSB PI-3 kinase, MEI-41 and ESR-1
    COG5032
    Location:1772386
    TEL1; Phosphatidylinositol kinase or protein kinase, PI-3 family [Signal transduction mechanisms]
    cd00892
    Location:20512322
    PIKKc_ATR; Catalytic domain of Ataxia telangiectasia and Rad3-related proteins
    pfam02260
    Location:23552386
    FATC; FATC domain
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