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msh2 DNA mismatch repair protein [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540695, updated on 6-Jan-2019

Summary

Gene symbol
msh2
Gene description
DNA mismatch repair protein
Locus tag
SPBC19G7.01c
Gene type
protein coding
RNA name
DNA mismatch repair protein
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
mut3; SPBC24C6.12c; swi8

Genomic context

See msh2 in Genome Data Viewer
Location:
chromosome: II
Exon count:
3
Sequence:
Chromosome: II; NC_003423.3 (2343653..2347813, complement)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene putative cytochrome c oxidase subunit VIb related protein Neighboring gene WISH/DIP/SPIN90 ortholog Dip1 Neighboring gene G10 protein Neighboring gene putative 4-amino-4-deoxychorismate lyase Neighboring gene HMG box protein Neighboring gene 40S ribosomal protein S30 Neighboring gene 1,3-beta-glucan synthase catalytic subunit Bgs1

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the msh2 gene: The msh2 gene is conserved in human, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, S.cerevisiae, K.lactis, E.gossypii, M.oryzae, N.crassa, A.thaliana, and frog.

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
ATP binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ATP binding ISO
Inferred from Sequence Orthology
more info
 
ATPase activity ISO
Inferred from Sequence Orthology
more info
 
DNA-dependent ATPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Y-form DNA binding ISO
Inferred from Sequence Orthology
more info
 
damaged DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
double-strand/single-strand DNA junction binding ISO
Inferred from Sequence Orthology
more info
 
contributes_to four-way junction DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
four-way junction DNA binding ISO
Inferred from Sequence Orthology
more info
 
contributes_to guanine/thymine mispair binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
contributes_to guanine/thymine mispair binding ISO
Inferred from Sequence Orthology
more info
 
contributes_to heteroduplex DNA loop binding ISO
Inferred from Sequence Orthology
more info
 
contributes_to single base insertion or deletion binding ISO
Inferred from Sequence Orthology
more info
 
contributes_to single thymine insertion binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
gene conversion at mating-type locus IMP
Inferred from Mutant Phenotype
more info
PubMed 
maintenance of DNA repeat elements IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
maintenance of DNA repeat elements IMP
Inferred from Mutant Phenotype
more info
PubMed 
mismatch repair IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mismatch repair IGI
Inferred from Genetic Interaction
more info
PubMed 
mismatch repair IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of DNA recombination IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
postreplication repair IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
MutSalpha complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
MutSbeta complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol HDA PubMed 
mismatch repair complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mismatch repair complex IEA
Inferred from Electronic Annotation
more info
 
nuclear chromosome ISO
Inferred from Sequence Orthology
more info
 
nucleus HDA PubMed 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
DNA mismatch repair protein

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    2343653..2347813 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001356256.1NP_001342761.1  DNA mismatch repair protein [Schizosaccharomyces pombe]

    Status: PROVISIONAL

    Conserved Domains (1) summary
    COG0249
    Location:9976
    MutS; DNA mismatch repair ATPase MutS [Replication, recombination and repair]
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