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mcm2 MCM complex subunit Mcm2 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2540620, updated on 6-Jan-2019

Summary

Gene symbol
mcm2
Gene description
MCM complex subunit Mcm2
Locus tag
SPBC4.04c
Gene type
protein coding
RNA name
MCM complex subunit Mcm2
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
cdc19; nda1

Genomic context

See mcm2 in Genome Data Viewer
Location:
chromosome: II
Exon count:
2
Sequence:
Chromosome: II; NC_003423.3 (1191208..1194204, complement)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene putative COPII-coated vesicle-associated protein Sfb3 Neighboring gene ubiquitin protein ligase E3 component mlo2 Neighboring gene putative acid phosphatase

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the mcm2 gene: The mcm2 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, M.oryzae, N.crassa, A.thaliana, rice, and frog.

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
contributes_to ATP-dependent DNA helicase activity ISO
Inferred from Sequence Orthology
more info
 
DNA replication origin binding ISO
Inferred from Sequence Orthology
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
mitotic DNA replication initiation IC
Inferred by Curator
more info
PubMed 
negative regulation of DNA helicase activity IEA
Inferred from Electronic Annotation
more info
 
negative regulation of helicase activity IDA
Inferred from Direct Assay
more info
PubMed 
premeiotic DNA replication IC
Inferred by Curator
more info
PubMed 
Component Evidence Code Pubs
DNA replication preinitiation complex IC
Inferred by Curator
more info
PubMed 
MCM complex IDA
Inferred from Direct Assay
more info
PubMed 
nuclear chromatin IDA
Inferred from Direct Assay
more info
PubMed 
nuclear chromosome, telomeric region IDA
Inferred from Direct Assay
more info
PubMed 
nuclear pre-replicative complex IC
Inferred by Curator
more info
PubMed 
nuclear replication fork IC
Inferred by Curator
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    1191208..1194204 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021388.2NP_595477.1  MCM complex subunit Mcm2 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_595477.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P40377
    Conserved Domains (4) summary
    smart00350
    Location:295810
    MCM; minichromosome maintenance proteins
    pfam12619
    Location:42187
    MCM2_N; Mini-chromosome maintenance protein 2
    pfam14551
    Location:203315
    MCM_N; MCM N-terminal domain
    cl21455
    Location:529668
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
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