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mlh1 putative MutL family protein Mlh1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2539949, updated on 8-Jul-2018
Gene symbol
mlh1
Gene description
putative MutL family protein Mlh1
Locus tag
SPBC1703.04
Gene type
protein coding
RNA name
putative MutL family protein Mlh1
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
See mlh1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
4
Sequence:
Chromosome: II; NC_003423.3 (2921150..2923544)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene putative Rnase P/MRP subunit Neighboring gene RSC complex subunit Rsc9 Neighboring gene ARM-like repeat-containing protein Neighboring gene putative RIO family protein kinase Neighboring gene miscRNA Neighboring gene F-box protein Pof10

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
ATPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ATPase activity IEA
Inferred from Electronic Annotation
more info
 
mismatched DNA binding IEA
Inferred from Electronic Annotation
more info
 
single-stranded DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
mismatch repair IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mismatch repair TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
MutLalpha complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
chiasma IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol HDA PubMed 
mismatch repair complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mismatch repair complex IEA
Inferred from Electronic Annotation
more info
 
mitotic spindle pole body HDA PubMed 
nucleus HDA PubMed 
synaptonemal complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Preferred Names
putative MutL family protein Mlh1

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    2921150..2923544
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001022118.2NP_596199.1  putative MutL family protein Mlh1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_596199.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q9P7W6
    Conserved Domains (4) summary
    COG0323
    Location:7684
    MutL; DNA mismatch repair ATPase MutL [Replication, recombination and repair]
    cd03483
    Location:220346
    MutL_Trans_MLH1; MutL_Trans_MLH1: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to yeast and human MLH1 (MutL homologue 1). This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is known to ...
    pfam16413
    Location:445684
    Mlh1_C; DNA mismatch repair protein Mlh1 C-terminus
    cl00075
    Location:29156
    HATPase_c; Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins
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