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fnx1 vacuolar amino acid transmembrane transporter Fnx1 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2539786, updated on 18-Sep-2024

Summary

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Official Symbol
fnx1
Official Full Name
vacuolar amino acid transmembrane transporter Fnx1
Primary source
PomBase:SPBC12C2.13c
Locus tag
SPOM_SPBC12C2.13C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
SPBC21D10.04c
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Genomic context

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See fnx1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003423.3 (2444295..2446292)

Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene 5S ribosomal RNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene glyoxalase I glo1 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003423.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Avt5p is required for vacuolar uptake of amino acids in the fission yeast Schizosaccharomyces pombe. Chardwiriyapreecha S, et al. FEBS Lett, 2010 Jun 3. PMID 20388511
  2. Identification of the fnx1+ and fnx2+ genes for vacuolar amino acid transporters in Schizosaccharomyces pombe. Chardwiriyapreecha S, et al. FEBS Lett, 2008 Jun 25. PMID 18503766
  3. Clr4/Suv39 and RNA quality control factors cooperate to trigger RNAi and suppress antisense RNA. Zhang K, et al. Science, 2011 Mar 25. PMID 21436456, Free PMC Article
  4. High-Throughput Identification of Nuclear Envelope Protein Interactions in Schizosaccharomyces pombe Using an Arrayed Membrane Yeast-Two Hybrid Library. Varberg JM, et al. G3 (Bethesda), 2020 Dec 3. PMID 33109728, Free PMC Article
  5. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. These results suggest that fnx1(+) and fnx2(+) are involved in vacuolar amino acid uptake in S. pombe.
    Title: Identification of the fnx1+ and fnx2+ genes for vacuolar amino acid transporters in Schizosaccharomyces pombe.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables L-asparagine transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables L-isoleucine transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables L-lysine transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables basic amino acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in L-lysine import into vacuole involved in cellular response to nitrogen starvation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in asparagine transmembrane import into vacuole IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in basic amino acid transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in isoleucine transmembrane transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in fungal-type vacuole HDA PubMed 
is_active_in fungal-type vacuole membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in fungal-type vacuole membrane IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
vacuolar amino acid transmembrane transporter Fnx1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003423.3 Reference assembly

    Range
    2444295..2446292
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001021917.3 → NP_596009.1  vacuolar amino acid transmembrane transporter Fnx1 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_596009.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q09752, Q9URP7, Q9USV8, Q9UTY2
    Conserved Domains (2) summary
    cd06174
    Location:34 → 443
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    pfam07690
    Location:37 → 439
    MFS_1; Major Facilitator Superfamily
Nucleotide Protein
Heading Accession and Version

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