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prp4 serine/threonine protein kinase Prp4 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2539312, updated on 18-Sep-2024
Official Symbol
prp4
Official Full Name
serine/threonine protein kinase Prp4
Primary source
PomBase:SPCC777.14
Locus tag
SPOM_SPCC777.14
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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See prp4 in Genome Data Viewer
Location:
chromosome: III
Exon count:
2
Sequence:
Chromosome: III; NC_003421.2 (1622499..1624475)

Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene retromer complex subunit Vps35 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene tRNA dihydrouridine synthase Dus4 Neighboring gene protein phosphatase regulatory subunit Ekc1 Neighboring gene ncRNA Neighboring gene wtf element Wtf14

Genomic Sequence:
NC_003421.2

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Prp4 Kinase Grants the License to Splice: Control of Weak Splice Sites during Spliceosome Activation. Eckert D, et al. PLoS Genet, 2016 Jan. PMID 26730850, Free PMC Article
  2. Prp4 kinase is required for proper segregation of chromosomes during meiosis in Schizosaccharomyces pombe. Pozgajova M, et al. Acta Biochim Pol, 2013. PMID 24432349
  3. The prp1+ gene required for pre-mRNA splicing in Schizosaccharomyces pombe encodes a protein that contains TPR motifs and is similar to Prp6p of budding yeast. Urushiyama S, et al. Genetics, 1997 Sep. PMID 9286671, Free PMC Article
  4. Identification and characterization of srp1, a gene of fission yeast encoding a RNA binding domain and a RS domain typical of SR splicing factors. Gross T, et al. Nucleic Acids Res, 1998 Jan 15. PMID 9421507, Free PMC Article
  5. Fission yeast Prp4p kinase regulates pre-mRNA splicing by phosphorylating a non-SR-splicing factor. Schwelnus W, et al. EMBO Rep, 2001 Jan. PMID 11252721, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein serine/threonine kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in mRNA cis splicing, via spliceosome IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of mRNA cis splicing, via spliceosome IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in signaling IC
Inferred by Curator
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
Preferred Names
serine/threonine protein kinase Prp4

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003421.2 Reference assembly

    Range
    1622499..1624475
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001023251.3 → NP_588261.1  serine/threonine protein kinase Prp4 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_588261.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P87202, Q07538
    Conserved Domains (2) summary
    smart00220
    Location:159 → 474
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14135
    Location:158 → 474
    STKc_PRP4; Catalytic domain of the Serine/Threonine Kinase, Pre-mRNA-Processing factor 4
Nucleotide Protein
Heading Accession and Version

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