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tif6 translation initiation factor-like ribosome biogenesis protein [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2539126, updated on 19-Nov-2025
Official Symbol
tif6
Official Full Name
translation initiation factor-like ribosome biogenesis protein
Primary source
PomBase:SPCC1919.09
Locus tag
SPOM_SPCC1919.09
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Location:
chromosome: III
Exon count:
3
Sequence:
Chromosome: III; NC_003421.2 (2223148..2224470)

Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene wtf antidote-like meiotic drive suppressor Wtf25 Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene mitochondrial 54S ribosomal protein uL30m Neighboring gene ncRNA Neighboring gene myosin type V Neighboring gene ncRNA

Genomic Sequence:
NC_003421.2

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Clr4/Suv39 and RNA quality control factors cooperate to trigger RNAi and suppress antisense RNA. Zhang K, et al. Science, 2011 Mar 25. PMID 21436456, Free PMC Article
  2. Chromatin localization of nucleophosmin organizes ribosome biogenesis. Ugolini I, et al. Mol Cell, 2022 Dec 1. PMID 36423630, Free PMC Article
  3. Comprehensive proteomics analysis reveals new substrates and regulators of the fission yeast clp1/cdc14 phosphatase. Chen JS, et al. Mol Cell Proteomics, 2013 May. PMID 23297348, Free PMC Article
  4. Dual recruitment of Cdc48 (p97)-Ufd1-Npl4 ubiquitin-selective segregase by small ubiquitin-like modifier protein (SUMO) and ubiquitin in SUMO-targeted ubiquitin ligase-mediated genome stability functions. Nie M, et al. J Biol Chem, 2012 Aug 24. PMID 22730331, Free PMC Article
  5. Transcription and chromatin-based surveillance mechanism controls suppression of cryptic antisense transcription. Heo DH, et al. Cell Rep, 2021 Sep 7. PMID 34496258, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables ribosomal large subunit binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ribosomal large subunit binding IEA
Inferred from Electronic Annotation
more info
  
enables ribosome binding IEA
Inferred from Electronic Annotation
more info
  
enables translation initiation factor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in assembly of large subunit precursor of preribosome EXP
Inferred from Experiment
more info
 PubMed 
involved_in assembly of large subunit precursor of preribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cytosolic ribosome assembly IEA
Inferred from Electronic Annotation
more info
  
involved_in maturation of 5.8S rRNA IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in maturation of LSU-rRNA IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ribosomal large subunit biogenesis IEA
Inferred from Electronic Annotation
more info
  
involved_in ribosomal subunit export from nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ribosomal subunit export from nucleus IEA
Inferred from Electronic Annotation
more info
  
involved_in ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
  
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
involved_in translational initiation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytosol HDA PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of preribosome IDA
Inferred from Direct Assay
more info
 PubMed 
Preferred Names
translation initiation factor-like ribosome biogenesis protein

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003421.2 Reference assembly

    Range
    2223148..2224470
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001023481.3 → NP_588491.1  translation initiation factor-like ribosome biogenesis protein [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_588491.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O94476
    Conserved Domains (1) summary
    PTZ00136
    Location:1 → 243
    PTZ00136; eukaryotic translation initiation factor 6-like protein; Provisional
Nucleotide Protein
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Molecular Biology Databases
Research Materials