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ZNF620 zinc finger protein 620 [ Homo sapiens (human) ]

Gene ID: 253639, updated on 21-Dec-2019

Summary

Official Symbol
ZNF620provided by HGNC
Official Full Name
zinc finger protein 620provided by HGNC
Primary source
HGNC:HGNC:28742
See related
Ensembl:ENSG00000177842
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Low expression observed in reference dataset See more
Orthologs

Genomic context

See ZNF620 in Genome Data Viewer
Location:
3p22.1
Exon count:
8
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 3 NC_000003.12 (40502604..40518736)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (40547450..40559712)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene zinc finger protein 619 Neighboring gene RNA, U5B small nuclear 2, pseudogene Neighboring gene zinc finger protein 621 Neighboring gene ribosomal protein L5 pseudogene 10

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC50836

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001256167.1NP_001243096.1  zinc finger protein 620 isoform b

    See identical proteins and their annotated locations for NP_001243096.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks two alternate exons in the 5' coding region and uses a downstream start codon, compared to variant 1. The encoded isoform (b) is shorter at the N-terminus, compared to isoform a. Both variants 2 and 3 encode isoform b.
    Source sequence(s)
    AK093599, BC044953, BY800121, DA172830
    Consensus CDS
    CCDS58825.1
    UniProtKB/Swiss-Prot
    Q6ZNG0
    Related
    ENSP00000391472.1, ENST00000418905.1
    Conserved Domains (3) summary
    COG5048
    Location:108252
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:196216
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:236261
    zf-H2C2_2; Zinc-finger double domain
  2. NM_001256168.1NP_001243097.1  zinc finger protein 620 isoform b

    See identical proteins and their annotated locations for NP_001243097.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR, lacks two alternate exons in the 5' coding region and uses a downstream start codon, compared to variant 1. The encoded isoform (b) is shorter at the N-terminus, compared to isoform a. Both variants 2 and 3 encode isoform b.
    Source sequence(s)
    BC044953, BY800121, DA613081
    Consensus CDS
    CCDS58825.1
    UniProtKB/Swiss-Prot
    Q6ZNG0
    Conserved Domains (3) summary
    COG5048
    Location:108252
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:196216
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:236261
    zf-H2C2_2; Zinc-finger double domain
  3. NM_175888.4NP_787084.1  zinc finger protein 620 isoform a

    See identical proteins and their annotated locations for NP_787084.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a).
    Source sequence(s)
    AC121754, AK131232, BC044953, BY800121
    Consensus CDS
    CCDS33740.1
    UniProtKB/Swiss-Prot
    Q6ZNG0
    UniProtKB/TrEMBL
    A0A024R2M2
    Related
    ENSP00000322265.6, ENST00000314529.10
    Conserved Domains (5) summary
    smart00349
    Location:1170
    KRAB; krueppel associated box
    COG5048
    Location:222366
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:310330
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:1150
    KRAB; KRAB box
    pfam13465
    Location:350375
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

    Range
    40502604..40518736
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017006069.2XP_016861558.1  zinc finger protein 620 isoform X6

    UniProtKB/Swiss-Prot
    Q6ZNG0
    Conserved Domains (3) summary
    COG5048
    Location:108252
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:196216
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:236261
    zf-H2C2_2; Zinc-finger double domain
  2. XM_017006064.2XP_016861553.1  zinc finger protein 620 isoform X1

  3. XM_005265011.4XP_005265068.1  zinc finger protein 620 isoform X2

    See identical proteins and their annotated locations for XP_005265068.1

    UniProtKB/Swiss-Prot
    Q6ZNG0
    UniProtKB/TrEMBL
    A0A024R2M2
    Conserved Domains (5) summary
    smart00349
    Location:1170
    KRAB; krueppel associated box
    COG5048
    Location:222366
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:310330
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:1150
    KRAB; KRAB box
    pfam13465
    Location:350375
    zf-H2C2_2; Zinc-finger double domain
  4. XM_017006065.2XP_016861554.1  zinc finger protein 620 isoform X3

  5. XM_017006066.2XP_016861555.1  zinc finger protein 620 isoform X4

    Conserved Domains (3) summary
    COG5048
    Location:183327
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:271291
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:311336
    zf-H2C2_2; Zinc-finger double domain
  6. XM_005265012.4XP_005265069.1  zinc finger protein 620 isoform X2

    See identical proteins and their annotated locations for XP_005265069.1

    UniProtKB/Swiss-Prot
    Q6ZNG0
    UniProtKB/TrEMBL
    A0A024R2M2
    Conserved Domains (5) summary
    smart00349
    Location:1170
    KRAB; krueppel associated box
    COG5048
    Location:222366
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:310330
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:1150
    KRAB; KRAB box
    pfam13465
    Location:350375
    zf-H2C2_2; Zinc-finger double domain
  7. XM_017006068.2XP_016861557.1  zinc finger protein 620 isoform X5

  8. XM_017006067.2XP_016861556.1  zinc finger protein 620 isoform X4

    Conserved Domains (3) summary
    COG5048
    Location:183327
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:271291
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:311336
    zf-H2C2_2; Zinc-finger double domain
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