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Egr3 early growth response 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 25148, updated on 7-Aug-2021

Summary

Official Symbol
Egr3provided by RGD
Official Full Name
early growth response 3provided by RGD
Primary source
RGD:2545
See related
Ensembl:ENSRNOG00000017828
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
zinc finger transcription factor; may mediate long-term, neuroplastic responses [RGD, Feb 2006]
Expression
Biased expression in Brain (RPKM 21.0), Spleen (RPKM 13.1) and 6 other tissues See more
Orthologs
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Genomic context

See Egr3 in Genome Data Viewer
Location:
15p11
Exon count:
3
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (45150335..45156052)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (51756683..51762080)

Chromosome 15 - NC_051350.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102550955 Neighboring gene phosphatidylethanolamine binding protein 4 Neighboring gene uncharacterized LOC120097027 Neighboring gene bridging integrator 3 Neighboring gene cell cycle and apoptosis regulator 2

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
early growth response protein 3
Names
EGR-3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_017086.1NP_058782.1  early growth response protein 3

    See identical proteins and their annotated locations for NP_058782.1

    Status: PROVISIONAL

    Source sequence(s)
    U12428
    UniProtKB/Swiss-Prot
    P43301
    Related
    ENSRNOP00000024066.2, ENSRNOT00000024067.5
    Conserved Domains (4) summary
    COG5048
    Location:303375
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:277299
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:275299
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:319344
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051350.1 Reference mRatBN7.2 Primary Assembly

    Range
    45150335..45156052
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006252240.4XP_006252302.1  early growth response protein 3 isoform X1

    See identical proteins and their annotated locations for XP_006252302.1

    Conserved Domains (2) summary
    COG5048
    Location:265337
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:239261
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. XM_039093001.1XP_038948929.1  early growth response protein 3 isoform X1

    Conserved Domains (2) summary
    COG5048
    Location:265337
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:239261
    ZF_C2H2; C2H2 Zn finger [structural motif]
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