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Tagln transgelin [ Rattus norvegicus (Norway rat) ]

Gene ID: 25123, updated on 5-Aug-2018

Summary

Official Symbol
Taglnprovided by RGD
Official Full Name
transgelinprovided by RGD
Primary source
RGD:3723
See related
Ensembl:ENSRNOG00000017628
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Sm22
Summary
acts as an actin cross-linking protein [RGD, Feb 2006]
Expression
Biased expression in Uterus (RPKM 5700.2), Lung (RPKM 1185.4) and 6 other tissues See more
Orthologs

Genomic context

See Tagln in Genome Data Viewer
Location:
8q22
Exon count:
5
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (50222895..50228369, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 8 NC_005107.3 (48847354..48853081, complement)

Chromosome 8 - NC_005107.4Genomic Context describing neighboring genes Neighboring gene ring finger protein 214 Neighboring gene proprotein convertase subtilisin/kexin type 7 Neighboring gene SID1 transmembrane family, member 2 Neighboring gene platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 Neighboring gene similar to 40S ribosomal protein S26

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
actin filament binding IEA
Inferred from Electronic Annotation
more info
 
actin filament binding TAS
Traceable Author Statement
more info
PubMed 
protein binding, bridging TAS
Traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
NOT cytoskeleton organization ISO
Inferred from Sequence Orthology
more info
 
epithelial cell differentiation IEA
Inferred from Electronic Annotation
more info
 
epithelial cell differentiation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
transgelin
Names
SM22-alpha
smooth muscle 22 protein
smooth muscle protein 22-alpha

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_031549.2NP_113737.1  transgelin

    See identical proteins and their annotated locations for NP_113737.1

    Status: PROVISIONAL

    Source sequence(s)
    BC061770
    UniProtKB/Swiss-Prot
    P31232
    Related
    ENSRNOP00000024030.3, ENSRNOT00000024030.6
    Conserved Domains (3) summary
    COG5199
    Location:14189
    SCP1; Calponin [Cytoskeleton]
    cd00014
    Location:25137
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    pfam00402
    Location:175198
    Calponin; Calponin family repeat

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005107.4 Reference Rnor_6.0 Primary Assembly

    Range
    50222895..50228369 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000076.1 Alternate Rn_Celera

    Range
    45807491..45812962 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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