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Tagln transgelin [ Rattus norvegicus (Norway rat) ]

Gene ID: 25123, updated on 30-Sep-2021

Summary

Official Symbol
Taglnprovided by RGD
Official Full Name
transgelinprovided by RGD
Primary source
RGD:3723
See related
EnsemblRapid:ENSRNOG00000017628
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Sm22
Summary
acts as an actin cross-linking protein [RGD, Feb 2006]
Expression
Biased expression in Uterus (RPKM 5700.2), Lung (RPKM 1185.4) and 6 other tissues See more
Orthologs
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Genomic context

See Tagln in Genome Data Viewer
Location:
8q22
Exon count:
5
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (46224939..46230413, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (50222895..50228369, complement)

Chromosome 8 - NC_051343.1Genomic Context describing neighboring genes Neighboring gene ring finger protein 214 Neighboring gene proprotein convertase subtilisin/kexin type 7 Neighboring gene uncharacterized LOC120094332 Neighboring gene SID1 transmembrane family, member 2 Neighboring gene platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 Neighboring gene 40S ribosomal protein S26-like

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
 
enables actin filament binding TAS
Traceable Author Statement
more info
PubMed 
enables protein-macromolecule adaptor activity TAS
Traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
NOT acts_upstream_of_or_within cytoskeleton organization ISO
Inferred from Sequence Orthology
more info
 
involved_in epithelial cell differentiation IEA
Inferred from Electronic Annotation
more info
 
involved_in epithelial cell differentiation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
transgelin
Names
SM22-alpha
smooth muscle 22 protein
smooth muscle protein 22-alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_031549.2NP_113737.1  transgelin

    See identical proteins and their annotated locations for NP_113737.1

    Status: PROVISIONAL

    Source sequence(s)
    BC061770
    UniProtKB/Swiss-Prot
    P31232
    Related
    ENSRNOP00000069919.2, ENSRNOT00000081737.2
    Conserved Domains (2) summary
    pfam00402
    Location:175199
    Calponin; Calponin family repeat
    cd21279
    Location:23143
    CH_TAGLN; calponin homology (CH) domain found in transgelin

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051343.1 Reference mRatBN7.2 Primary Assembly

    Range
    46224939..46230413 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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