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Grpr gastrin releasing peptide receptor [ Rattus norvegicus (Norway rat) ]

Gene ID: 24938, updated on 13-Aug-2019

Summary

Official Symbol
Grprprovided by RGD
Official Full Name
gastrin releasing peptide receptorprovided by RGD
Primary source
RGD:2750
See related
Ensembl:ENSRNOG00000004124
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
G-protein coupled receptor for the mammalian bombesis peptide, may be involved in the development and/or maintenace of specific hindbrain segments [RGD, Feb 2006]
Expression
Biased expression in Uterus (RPKM 43.3), Kidney (RPKM 9.0) and 1 other tissue See more
Orthologs

Genomic context

See Grpr in Genome Data Viewer
Location:
Xq14
Exon count:
3
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (32746259..32786266)
104 previous assembly Rnor_5.0 (GCF_000001895.4) X NC_005120.3 (33083317..33123324)

Chromosome X - NC_005120.4Genomic Context describing neighboring genes Neighboring gene similar to RIKEN cDNA 1700045I19 Neighboring gene uncharacterized LOC103690819 Neighboring gene ribosomal protein S6-like Neighboring gene ribosomal protein L29 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
G protein-coupled peptide receptor activity ISO
Inferred from Sequence Orthology
more info
PubMed 
G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
G protein-coupled receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
bombesin receptor activity TAS
Traceable Author Statement
more info
PubMed 
neuropeptide binding IDA
Inferred from Direct Assay
more info
PubMed 
neuropeptide receptor activity ISO
Inferred from Sequence Orthology
more info
PubMed 
neuropeptide receptor activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
G protein-coupled receptor signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
bombesin receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
learning or memory IMP
Inferred from Mutant Phenotype
more info
PubMed 
motor behavior ISO
Inferred from Sequence Orthology
more info
PubMed 
motor behavior ISS
Inferred from Sequence or Structural Similarity
more info
 
neuropeptide signaling pathway IEA
Inferred from Electronic Annotation
more info
 
phospholipase C-activating G protein-coupled receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
PubMed 
phospholipase C-activating G protein-coupled receptor signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
 
psychomotor behavior IEA
Inferred from Electronic Annotation
more info
 
psychomotor behavior ISO
Inferred from Sequence Orthology
more info
PubMed 
regulation of cell proliferation IEA
Inferred from Electronic Annotation
more info
 
regulation of cell proliferation ISO
Inferred from Sequence Orthology
more info
PubMed 
response to external biotic stimulus IEA
Inferred from Electronic Annotation
more info
 
response to external biotic stimulus ISO
Inferred from Sequence Orthology
more info
PubMed 
social behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
social behavior ISO
Inferred from Sequence Orthology
more info
PubMed 
social behavior ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
integral component of plasma membrane ISO
Inferred from Sequence Orthology
more info
PubMed 
integral component of plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
membrane IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
gastrin-releasing peptide receptor
Names
GRP-R
GRP-preferring bombesin receptor

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_012706.2NP_036838.1  gastrin-releasing peptide receptor

    See identical proteins and their annotated locations for NP_036838.1

    Status: PROVISIONAL

    Source sequence(s)
    X56661
    UniProtKB/Swiss-Prot
    P52500
    Related
    ENSRNOP00000005559.4, ENSRNOT00000005559.6
    Conserved Domains (1) summary
    pfam00001
    Location:58321
    7tm_1; 7 transmembrane receptor (rhodopsin family)

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005120.4 Reference Rnor_6.0 Primary Assembly

    Range
    32746259..32786266
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000089.1 Alternate Rn_Celera

    Range
    31324305..31364289
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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