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Thy1 Thy-1 cell surface antigen [ Rattus norvegicus (Norway rat) ]

Gene ID: 24832, updated on 3-Jun-2018
Official Symbol
Thy1provided by RGD
Official Full Name
Thy-1 cell surface antigenprovided by RGD
Primary source
RGD:3860
See related
Ensembl:ENSRNOG00000006604
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
CD7
Summary
cell surface glycoprotein antigen [RGD, Feb 2006]
Expression
Biased expression in Thymus (RPKM 2242.5) and Brain (RPKM 1279.6) See more
Orthologs
See Thy1 in Genome Data Viewer
Location:
8q22
Exon count:
5
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (48382121..48387271)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 8 NC_005107.3 (46998623..47003773)

Chromosome 8 - NC_005107.4Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103693067 Neighboring gene uncharacterized LOC103693068 Neighboring gene ubiquitin specific peptidase 2 Neighboring gene membrane frizzled-related protein

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
GPI anchor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
GPI anchor binding IDA
Inferred from Direct Assay
more info
PubMed 
GTPase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
GTPase activator activity IDA
Inferred from Direct Assay
more info
PubMed 
enzyme binding IPI
Inferred from Physical Interaction
more info
PubMed 
integrin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
integrin binding ISO
Inferred from Sequence Orthology
more info
 
integrin binding ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein kinase binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein kinase binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
T cell receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
T cell receptor signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
angiogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
angiogenesis ISO
Inferred from Sequence Orthology
more info
 
angiogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
cell-cell adhesion IMP
Inferred from Mutant Phenotype
more info
PubMed 
cell-cell signaling IDA
Inferred from Direct Assay
more info
PubMed 
cell-cell signaling ISO
Inferred from Sequence Orthology
more info
 
cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoskeleton organization IDA
Inferred from Direct Assay
more info
PubMed 
focal adhesion assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
focal adhesion assembly IDA
Inferred from Direct Assay
more info
PubMed 
integrin-mediated signaling pathway ISO
Inferred from Sequence Orthology
more info
 
integrin-mediated signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
mast cell activation NAS
Non-traceable Author Statement
more info
PubMed 
negative regulation of T cell receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
negative regulation of T cell receptor signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of apoptotic process TAS
Traceable Author Statement
more info
PubMed 
negative regulation of axonogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of axonogenesis IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of cell migration IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of cell migration IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of fibroblast proliferation NAS
Non-traceable Author Statement
more info
PubMed 
negative regulation of neuron projection regeneration IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of neuron projection regeneration ISO
Inferred from Sequence Orthology
more info
 
negative regulation of protein kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of protein kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of protein tyrosine kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of GTPase activity IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of T cell activation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of T cell activation IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of cellular extravasation IEA
Inferred from Electronic Annotation
more info
 
positive regulation of cellular extravasation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of focal adhesion assembly ISO
Inferred from Sequence Orthology
more info
 
positive regulation of focal adhesion assembly ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
positive regulation of heterotypic cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 
positive regulation of heterotypic cell-cell adhesion ISO
Inferred from Sequence Orthology
more info
 
positive regulation of peptidyl-tyrosine phosphorylation NAS
Non-traceable Author Statement
more info
PubMed 
positive regulation of release of sequestered calcium ion into cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of release of sequestered calcium ion into cytosol IDA
Inferred from Direct Assay
more info
PubMed 
protein autophosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
receptor clustering IDA
Inferred from Direct Assay
more info
PubMed 
regulation of Rho-dependent protein serine/threonine kinase activity ISO
Inferred from Sequence Orthology
more info
 
regulation of Rho-dependent protein serine/threonine kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
regulation of cell-matrix adhesion ISO
Inferred from Sequence Orthology
more info
 
retinal cone cell development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
retinal cone cell development ISO
Inferred from Sequence Orthology
more info
 
retinal cone cell development ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
anchored component of external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
anchored component of external side of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
anchored component of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
apical plasma membrane IEA
Inferred from Electronic Annotation
more info
 
apical plasma membrane ISO
Inferred from Sequence Orthology
more info
 
axolemma IDA
Inferred from Direct Assay
more info
PubMed 
cell surface IDA
Inferred from Direct Assay
more info
PubMed 
cell surface ISO
Inferred from Sequence Orthology
more info
 
cell surface TAS
Traceable Author Statement
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
dendrite IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
dendrite ISO
Inferred from Sequence Orthology
more info
 
dendrite membrane IDA
Inferred from Direct Assay
more info
PubMed 
endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
external side of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
external side of plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
growth cone IDA
Inferred from Direct Assay
more info
PubMed 
membrane raft IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
membrane raft IDA
Inferred from Direct Assay
more info
PubMed 
membrane raft ISO
Inferred from Sequence Orthology
more info
 
myelin sheath IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
myelin sheath ISO
Inferred from Sequence Orthology
more info
 
neuronal cell body membrane IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
thy-1 membrane glycoprotein
Names
CD90
Thy-1 protein
Thymus cell surface antigen
thy-1 antigen
thy-1 glycoprotein
thymus cell antigen 1, theta

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_012673.2NP_036805.1  thy-1 membrane glycoprotein preproprotein

    See identical proteins and their annotated locations for NP_036805.1

    Status: VALIDATED

    Source sequence(s)
    CB741211, CB797376, CO561977, X03150
    UniProtKB/Swiss-Prot
    P01830
    Related
    ENSRNOP00000008685.1, ENSRNOT00000008685.3
    Conserved Domains (2) summary
    smart00410
    Location:30116
    IG_like; Immunoglobulin like
    cl11960
    Location:22116
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005107.4 Reference Rnor_6.0 Primary Assembly

    Range
    48382121..48387271
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017595476.1XP_017450965.1  thy-1 membrane glycoprotein isoform X1

Alternate Rn_Celera

Genomic

  1. AC_000076.1 Alternate Rn_Celera

    Range
    43976742..43981520
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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