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Prm1 protamine 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 24685, updated on 13-Apr-2024

Summary

Official Symbol
Prm1provided by RGD
Official Full Name
protamine 1provided by RGD
Primary source
RGD:1583873
See related
AllianceGenome:RGD:1583873
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable DNA binding activity. Predicted to be involved in chromosome condensation. Predicted to act upstream of or within nucleus organization and spermatid development. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of nucleosome. Orthologous to human PRM1 (protamine 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward (RPKM 8501.2) See more
Orthologs
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Genomic context

Location:
10q11
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (5378740..5379235)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (4871817..4872312)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (4945995..4946241)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102552269 Neighboring gene RecQ mediated genome instability 2 Neighboring gene protamine 2 Neighboring gene protamine 3

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in chromosome condensation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within nucleus organization ISO
Inferred from Sequence Orthology
more info
 
involved_in sperm DNA condensation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within spermatid development ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
NOT located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in male germ cell nucleus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
part_of nucleosome IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
sperm protamine P1
Names
cysteine-rich protamine
protamine P1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001002850.2NP_001002850.1  sperm protamine P1

    See identical proteins and their annotated locations for NP_001002850.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000010
    UniProtKB/Swiss-Prot
    A0JN03, P10118
    UniProtKB/TrEMBL
    A6K4I5

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    5378740..5379235
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)