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Adig adipogenin [ Mus musculus (house mouse) ]

Gene ID: 246747, updated on 8-Feb-2024

Summary

Official Symbol
Adigprovided by MGI
Official Full Name
adipogeninprovided by MGI
Primary source
MGI:MGI:2675492
See related
Ensembl:ENSMUSG00000044405 AllianceGenome:MGI:2675492
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Smaf1; SMAF-1
Summary
Involved in positive regulation of fat cell differentiation. Acts upstream of or within brown fat cell differentiation; spermatogenesis; and white fat cell differentiation. Located in cytoplasm; lipid droplet; and nucleus. Is expressed in gut and male reproductive gland or organ. Orthologous to human ADIG (adipogenin). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in mammary gland adult (RPKM 120.5), subcutaneous fat pad adult (RPKM 116.2) and 7 other tissues See more
Orthologs
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Genomic context

See Adig in Genome Data Viewer
Location:
2 H1; 2 78.72 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (158344532..158350118)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (158502612..158508198)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene Ral GTPase activating protein, beta subunit (non-catalytic) Neighboring gene predicted gene 14200 Neighboring gene predicted gene, 54127 Neighboring gene Rho GTPase activating protein 40 Neighboring gene predicted gene 14204 Neighboring gene solute carrier family 32 (GABA vesicular transporter), member 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 
  • Endonuclease-mediated (1) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in brown fat cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in brown fat cell differentiation IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in fat cell differentiation IEA
Inferred from Electronic Annotation
more info
 
NOT acts_upstream_of_or_within positive regulation of fat cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of fat cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in spermatogenesis IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in white fat cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in white fat cell differentiation IEP
Inferred from Expression Pattern
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in lipid droplet IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in lipid droplet IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
adipogenin
Names
small adipocyte factor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145635.2NP_663610.1  adipogenin

    See identical proteins and their annotated locations for NP_663610.1

    Status: VALIDATED

    Source sequence(s)
    AK131610, AY092026, BE624674
    Consensus CDS
    CCDS16990.1
    UniProtKB/Swiss-Prot
    Q8R400
    Related
    ENSMUSP00000051732.4, ENSMUST00000059889.4
    Conserved Domains (1) summary
    pfam15202
    Location:179
    Adipogenin; Adipogenin

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    158344532..158350118
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)