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Pgk1 phosphoglycerate kinase 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 24644, updated on 17-Nov-2020

Summary

Official Symbol
Pgk1provided by RGD
Official Full Name
phosphoglycerate kinase 1provided by RGD
Primary source
RGD:619878
See related
Ensembl:ENSRNOG00000058249
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Pgk
Summary
kinase enzyme that is important for phosphoprotein glycolysis [RGD, Feb 2006]
Expression
Biased expression in Muscle (RPKM 4387.2), Heart (RPKM 1744.3) and 7 other tissues See more
Orthologs

Genomic context

See Pgk1 in Genome Data Viewer
Location:
Xq22
Exon count:
11
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (77263399..77279373)
106 current Rn_Celera (GCF_000002265.2) X AC_000089.1 (72583654..72599628)
104 previous assembly Rnor_5.0 (GCF_000001895.4) X NC_005120.3 (56383459..56399433)

Chromosome X - NC_005120.4Genomic Context describing neighboring genes Neighboring gene toll-like receptor 13 Neighboring gene similar to ribosomal protein L19 Neighboring gene TATA-box binding protein associated factor 9b Neighboring gene 40S ribosomal protein S21-like

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC105265

Gene Ontology Provided by RGD

Function Evidence Code Pubs
ADP binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ADP binding IDA
Inferred from Direct Assay
more info
PubMed 
ATP binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ATP binding IEA
Inferred from Electronic Annotation
more info
 
ATP binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
ATP binding ISS
Inferred from Sequence or Structural Similarity
more info
 
phosphoglycerate kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phosphoglycerate kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
phosphoglycerate kinase activity IEA
Inferred from Electronic Annotation
more info
 
phosphoglycerate kinase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
phosphoglycerate kinase activity ISO
Inferred from Sequence Orthology
more info
 
phosphoglycerate kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
protein-disulfide reductase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
carbohydrate metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
cellular response to hypoxia ISO
Inferred from Sequence Orthology
more info
 
epithelial cell differentiation ISO
Inferred from Sequence Orthology
more info
 
gluconeogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
gluconeogenesis IDA
Inferred from Direct Assay
more info
PubMed 
gluconeogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
glycolytic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
glycolytic process IDA
Inferred from Direct Assay
more info
PubMed 
glycolytic process IEA
Inferred from Electronic Annotation
more info
 
glycolytic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
glycolytic process ISO
Inferred from Sequence Orthology
more info
 
negative regulation of angiogenesis ISO
Inferred from Sequence Orthology
more info
 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
phosphorylation ISS
Inferred from Sequence or Structural Similarity
more info
 
plasminogen activation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of oxidative phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
extracellular space ISO
Inferred from Sequence Orthology
more info
 
membrane raft ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
phosphoglycerate kinase 1
NP_445743.2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_053291.3NP_445743.2  phosphoglycerate kinase 1

    See identical proteins and their annotated locations for NP_445743.2

    Status: VALIDATED

    Source sequence(s)
    BC087651
    UniProtKB/Swiss-Prot
    P16617
    Related
    ENSRNOP00000073523.1, ENSRNOT00000077604.1
    Conserved Domains (1) summary
    PTZ00005
    Location:3416
    PTZ00005; phosphoglycerate kinase; Provisional

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005120.4 Reference Rnor_6.0 Primary Assembly

    Range
    77263399..77279373
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000089.1 Alternate Rn_Celera

    Range
    72583654..72599628
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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