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Chodl chondrolectin [ Mus musculus (house mouse) ]

Gene ID: 246048, updated on 21-Dec-2022

Summary

Official Symbol
Chodlprovided by MGI
Official Full Name
chondrolectinprovided by MGI
Primary source
MGI:MGI:2179069
See related
Ensembl:ENSMUSG00000022860 AllianceGenome:MGI:2179069
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
MT75; PRED12; 3110074E07Rik
Summary
Predicted to enable carbohydrate binding activity. Acts upstream of or within regulation of neuron projection development. Predicted to be located in centrosome; cytosol; and perinuclear region of cytoplasm. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and respiratory system. Orthologous to human CHODL (chondrolectin). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in limb E14.5 (RPKM 14.3), bladder adult (RPKM 7.6) and 4 other tissues See more
Orthologs
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Genomic context

See Chodl in Genome Data Viewer
Location:
16; 16 C3.1
Exon count:
7
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (78727729..78748624)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (78930841..78951736)

Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 24861 Neighboring gene RIKEN cDNA 4930570E03 gene Neighboring gene transmembrane protease, serine 15 Neighboring gene aldo-keto reductase family 1, member D1 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2)  1 citation
  • Endonuclease-mediated (4) 

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
 
NOT enables hyaluronic acid binding ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within nervous system development IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of axonogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within regulation of neuron projection development IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in centrosome ISO
Inferred from Sequence Orthology
more info
 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in perinuclear region of cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 

General protein information

Preferred Names
chondrolectin
Names
transmembrane protein MT75

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001362555.1NP_001349484.1  chondrolectin isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AC114925, AC161815
    Consensus CDS
    CCDS88954.1
    UniProtKB/TrEMBL
    B7ZMQ3
    Related
    ENSMUSP00000156041.2, ENSMUST00000232415.2
    Conserved Domains (1) summary
    cl02432
    Location:28180
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
  2. NM_139134.5NP_624360.2  chondrolectin isoform 1 precursor

    See identical proteins and their annotated locations for NP_624360.2

    Status: VALIDATED

    Source sequence(s)
    AC114925, AC161815
    Consensus CDS
    CCDS28279.1
    UniProtKB/Swiss-Prot
    Q8VI31, Q9CXM0
    UniProtKB/TrEMBL
    A0A8C6MQY1
    Related
    ENSMUSP00000023568.8, ENSMUST00000023568.14
    Conserved Domains (1) summary
    cl02432
    Location:28180
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000082.7 Reference GRCm39 C57BL/6J

    Range
    78727729..78748624
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006523030.4XP_006523093.1  chondrolectin isoform X1

    See identical proteins and their annotated locations for XP_006523093.1

    UniProtKB/Swiss-Prot
    Q9CXM0
    Related
    ENSMUSP00000063961.7, ENSMUST00000069148.13
    Conserved Domains (1) summary
    cl02432
    Location:28180
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
  2. XM_006523031.4XP_006523094.1  chondrolectin isoform X2

    Conserved Domains (1) summary
    cl02432
    Location:28180
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
  3. XM_006523032.3XP_006523095.1  chondrolectin isoform X3

    Conserved Domains (1) summary
    cl02432
    Location:28180
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain