Format

Send to:

Choose Destination

ATP6V0D2 ATPase H+ transporting V0 subunit d2 [ Homo sapiens (human) ]

Gene ID: 245972, updated on 23-Nov-2021

Summary

Official Symbol
ATP6V0D2provided by HGNC
Official Full Name
ATPase H+ transporting V0 subunit d2provided by HGNC
Primary source
HGNC:HGNC:18266
See related
Ensembl:ENSG00000147614 MIM:618072
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
VMA6; ATP6D2
Expression
Biased expression in kidney (RPKM 22.7) and colon (RPKM 1.1) See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See ATP6V0D2 in Genome Data Viewer
Location:
8q21.3
Exon count:
8
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 8 NC_000008.11 (86098910..86154225)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (87111139..87166454)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene ribosomal protein L32 pseudogene 4 Neighboring gene protein serine kinase H2 Neighboring gene uncharacterized LOC105375623 Neighboring gene solute carrier family 7 member 13

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
Genome-wide mapping for clinically relevant predictors of lamotrigine- and phenytoin-induced hypersensitivity reactions.
GeneReviews: Not available

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ38708

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables proton transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of macroautophagy NAS
Non-traceable Author Statement
more info
PubMed 
involved_in vacuolar acidification IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in vacuolar transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
V-type proton ATPase subunit d 2
Names
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
V-ATPase subunit d 2
vacuolar proton pump subunit d 2
NP_689778.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_152565.1NP_689778.1  V-type proton ATPase subunit d 2

    See identical proteins and their annotated locations for NP_689778.1

    Status: VALIDATED

    Source sequence(s)
    AK096027
    Consensus CDS
    CCDS6241.1
    UniProtKB/Swiss-Prot
    Q8N8Y2
    UniProtKB/TrEMBL
    A0A024R991
    Related
    ENSP00000285393.3, ENST00000285393.4
    Conserved Domains (1) summary
    pfam01992
    Location:16338
    vATP-synt_AC39; ATP synthase (C/AC39) subunit

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p13 Primary Assembly

    Range
    86098910..86154225
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center