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Ppp4r3c1 protein phosphatase 4 regulatory subunit 3C1 [ Mus musculus (house mouse) ]

Gene ID: 245511, updated on 18-Sep-2024

Summary

Official Symbol
Ppp4r3c1provided by MGI
Official Full Name
protein phosphatase 4 regulatory subunit 3C1provided by MGI
Primary source
MGI:MGI:3588286
See related
Ensembl:ENSMUSG00000035387 AllianceGenome:MGI:3588286
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Smek3p; Ppp4r3c; Ppp4r3cp; 4930415L06Rik
Summary
Orthologous to human PPP4R3C (protein phosphatase 4 regulatory subunit 3C). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
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Genomic context

See Ppp4r3c1 in Genome Data Viewer
Location:
X C1; X 39.95 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (88973703..88976458, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (89930097..89932852, complement)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_47523 Neighboring gene splicing factor, arginine/serine-rich 2, interacting protein pseudogene Neighboring gene STARR-seq mESC enhancer starr_47524 Neighboring gene Nanog pseudogene 1 Neighboring gene STARR-seq mESC enhancer starr_47525 Neighboring gene STARR-seq mESC enhancer starr_47526 Neighboring gene NSA2 ribosome biogenesis homolog pseudogene Neighboring gene hemogen like

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General gene information

Clone Names

  • MGC183898, MGC183900

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein phosphatase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein phosphatase regulator activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in DNA damage response IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in regulation of double-strand break repair IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of protein phosphatase 4 complex IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
protein PPP4R3C1
Names
Smek homolog 3
protein PPP4R3C
putative SMEK homolog 3
serine/threonine-protein phosphatase 4 regulatory subunit 3C

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033880.3NP_001029052.2  protein PPP4R3C1

    See identical proteins and their annotated locations for NP_001029052.2

    Status: VALIDATED

    Source sequence(s)
    AK132812, AL672285
    Consensus CDS
    CCDS53129.1
    UniProtKB/Swiss-Prot
    A2AG62, Q3V0Y1
    UniProtKB/TrEMBL
    B2RX57
    Related
    ENSMUSP00000085471.3, ENSMUST00000088146.3
    Conserved Domains (2) summary
    pfam04802
    Location:178369
    SMK-1; Component of IIS longevity pathway SMK-1
    cl17171
    Location:1783
    PH-like; Pleckstrin homology-like domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    88973703..88976458 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NR_003621.1: Suppressed sequence

    Description
    NR_003621.1: This RefSeq was permanently suppressed because it is now thought that this gene does encode a protein.