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Lalba lactalbumin, alpha [ Rattus norvegicus (Norway rat) ]

Gene ID: 24528, updated on 2-Oct-2018

Summary

Official Symbol
Lalbaprovided by RGD
Official Full Name
lactalbumin, alphaprovided by RGD
Primary source
RGD:2987
See related
Ensembl:ENSRNOG00000010811
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
regulatory subunit of lactose synthase found in milk; involved in altering substrate specificity of galactosyltransferase [RGD, Feb 2006]
Expression
Biased expression in Muscle (RPKM 5.1), Testes (RPKM 4.0) and 1 other tissue See more
Orthologs

Genomic context

See Lalba in Genome Data Viewer
Location:
7q36
Exon count:
5
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (140088420..140096347, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 7 NC_005106.3 (139231203..139233459, complement)

Chromosome 7 - NC_005106.4Genomic Context describing neighboring genes Neighboring gene olfactory receptor pseudogene 1109 Neighboring gene olfactory receptor pseudogene 1110 Neighboring gene olfactory receptor 1111 Neighboring gene uncharacterized LOC103692975 Neighboring gene KAT8 regulatory NSL complex subunit 2

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
calcium ion binding IEA
Inferred from Electronic Annotation
more info
 
lactose synthase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
defense response to Gram-negative bacterium IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
defense response to Gram-positive bacterium IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
lactose biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
extracellular region IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
alpha-lactalbumin
Names
lactose synthase B protein
NP_036726.1
XP_017450147.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_012594.1NP_036726.1  alpha-lactalbumin precursor

    See identical proteins and their annotated locations for NP_036726.1

    Status: PROVISIONAL

    Source sequence(s)
    X00461
    UniProtKB/Swiss-Prot
    P00714
    Related
    ENSRNOP00000014457.1, ENSRNOT00000014456.3
    Conserved Domains (1) summary
    pfam00062
    Location:20137
    Lys; C-type lysozyme/alpha-lactalbumin family

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005106.4 Reference Rnor_6.0 Primary Assembly

    Range
    140088420..140096347 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017594658.1XP_017450147.1  alpha-lactalbumin isoform X1

    UniProtKB/TrEMBL
    F1M7M1
    Conserved Domains (1) summary
    pfam00062
    Location:20137
    Lys; C-type lysozyme/alpha-lactalbumin family

Alternate Rn_Celera

Genomic

  1. AC_000075.1 Alternate Rn_Celera

    Range
    126117233..126119018 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. NW_001091349.1 Alternate Rn_Celera

    Range
    2488..2621
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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