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Zfp937 zinc finger protein 937 [ Mus musculus (house mouse) ]

Gene ID: 245174, updated on 8-Feb-2024

Summary

Official Symbol
Zfp937provided by MGI
Official Full Name
zinc finger protein 937provided by MGI
Primary source
MGI:MGI:3644476
See related
Ensembl:ENSMUSG00000060336 AllianceGenome:MGI:3644476
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm4979; ZIPO-I; EG245174
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in genitourinary system. Orthologous to human ZNF101 (zinc finger protein 101) and ZNF699 (zinc finger protein 699). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in bladder adult (RPKM 1.1), CNS E11.5 (RPKM 1.0) and 25 other tissues See more
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Genomic context

See Zfp937 in Genome Data Viewer
Location:
2 G3; 2 74.15 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (150059997..150088658)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (150218077..150246738)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene 10770 Neighboring gene predicted gene, 52531 Neighboring gene zinc finger protein 1004 Neighboring gene STARR-seq mESC enhancer starr_05999 Neighboring gene STARR-seq mESC enhancer starr_06000 Neighboring gene zinc finger protein 1005 Neighboring gene RIKEN cDNA 3300002I08 gene Neighboring gene STARR-seq mESC enhancer starr_06001 Neighboring gene mitochondrial ribosomal protein L47 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
zinc finger protein family member
Names
zinc-finger protein in podocyte I

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001142411.2NP_001135883.1  zinc finger protein family member

    See identical proteins and their annotated locations for NP_001135883.1

    Status: VALIDATED

    Source sequence(s)
    AL831742, AL929042
    Consensus CDS
    CCDS50738.1
    UniProtKB/TrEMBL
    A2ANU7
    Related
    ENSMUSP00000073454.4, ENSMUST00000073782.4
    Conserved Domains (5) summary
    smart00349
    Location:457
    KRAB; krueppel associated box
    COG5048
    Location:86486
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:217237
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:443
    KRAB; KRAB box
    pfam13465
    Location:453476
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    150059997..150088658
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030251209.1XP_030107069.1  zinc finger protein family member isoform X1

    Conserved Domains (4) summary
    COG5048
    Location:121397
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:217237
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:444
    KRAB; KRAB box
    pfam13465
    Location:425450
    zf-H2C2_2; Zinc-finger double domain
  2. XM_030251210.1XP_030107070.1  zinc finger protein family member isoform X2

    Conserved Domains (4) summary
    COG5048
    Location:164393
    COG5048; FOG: Zn-finger [General function prediction only]
    COG5189
    Location:60150
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:185205
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:421446
    zf-H2C2_2; Zinc-finger double domain