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Itgb1 integrin subunit beta 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 24511, updated on 16-Oct-2021

Summary

Symbol
Itgb1provided by RGD
Full Name
integrin subunit beta 1provided by RGD
Primary source
RGD:2927
See related
EnsemblRapid:ENSRNOG00000010966
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
beta subunit of integrin receptor which binds collagen [RGD, Feb 2006]
Expression
Biased expression in Lung (RPKM 1593.5), Heart (RPKM 1215.7) and 9 other tissues See more
Orthologs
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Genomic context

See Itgb1 in Genome Data Viewer
Location:
19q12
Exon count:
17
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (56705123..56753199)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (61677512..61725537)

Chromosome 19 - NC_051354.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120098511 Neighboring gene uncharacterized LOC120098512 Neighboring gene uncharacterized LOC102548537 Neighboring gene neuropilin 1 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene U4 spliceosomal RNA

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
contributes_to C-X3-C chemokine binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables C-X3-C chemokine binding IEA
Inferred from Electronic Annotation
more info
 
contributes_to C-X3-C chemokine binding ISO
Inferred from Sequence Orthology
more info
 
contributes_to C-X3-C chemokine binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables actin binding IDA
Inferred from Direct Assay
more info
PubMed 
enables actin binding IEA
Inferred from Electronic Annotation
more info
 
enables actin binding ISO
Inferred from Sequence Orthology
more info
 
enables alpha-actinin binding IDA
Inferred from Direct Assay
more info
PubMed 
enables cell adhesion molecule binding ISO
Inferred from Sequence Orthology
more info
 
enables collagen binding IDA
Inferred from Direct Assay
more info
PubMed 
enables collagen binding involved in cell-matrix adhesion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables collagen binding involved in cell-matrix adhesion IEA
Inferred from Electronic Annotation
more info
 
enables collagen binding involved in cell-matrix adhesion ISO
Inferred from Sequence Orthology
more info
 
enables fibronectin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables fibronectin binding IDA
Inferred from Direct Assay
more info
PubMed 
enables fibronectin binding IEA
Inferred from Electronic Annotation
more info
 
enables fibronectin binding ISO
Inferred from Sequence Orthology
more info
 
enables integrin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables integrin binding IEA
Inferred from Electronic Annotation
more info
 
enables integrin binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables integrin binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables integrin binding ISO
Inferred from Sequence Orthology
more info
 
enables kinase binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables laminin binding IDA
Inferred from Direct Assay
more info
PubMed 
enables laminin binding IEA
Inferred from Electronic Annotation
more info
 
enables laminin binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
contributes_to laminin binding ISO
Inferred from Sequence Orthology
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protease binding IEA
Inferred from Electronic Annotation
more info
 
enables protease binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protease binding ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein domain specific binding IDA
Inferred from Direct Assay
more info
PubMed 
enables protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
 
enables protein heterodimerization activity ISO
Inferred from Sequence Orthology
more info
 
enables protein kinase binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein tyrosine kinase binding IEA
Inferred from Electronic Annotation
more info
 
enables protein tyrosine kinase binding ISO
Inferred from Sequence Orthology
more info
 
enables protein-containing complex binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables protein-containing complex binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein-containing complex binding ISO
Inferred from Sequence Orthology
more info
 
enables signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables signaling receptor binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in CD40 signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in CD40 signaling pathway ISO
Inferred from Sequence Orthology
more info
 
involved_in G1/S transition of mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within G1/S transition of mitotic cell cycle ISO
Inferred from Sequence Orthology
more info
 
involved_in axon extension IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within axon extension ISO
Inferred from Sequence Orthology
more info
 
involved_in basement membrane organization IEA
Inferred from Electronic Annotation
more info
 
involved_in basement membrane organization ISO
Inferred from Sequence Orthology
more info
 
involved_in bicellular tight junction assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in calcium-independent cell-matrix adhesion IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within calcium-independent cell-matrix adhesion ISO
Inferred from Sequence Orthology
more info
 
involved_in cardiac muscle cell differentiation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cardiac muscle cell differentiation ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within cardiac muscle tissue development ISO
Inferred from Sequence Orthology
more info
 
involved_in cell adhesion ISO
Inferred from Sequence Orthology
more info
 
involved_in cell adhesion mediated by integrin IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cell adhesion mediated by integrin IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in cell adhesion mediated by integrin ISO
Inferred from Sequence Orthology
more info
 
involved_in cell adhesion mediated by integrin ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in cell fate specification IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cell fate specification ISO
Inferred from Sequence Orthology
more info
 
involved_in cell migration IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within cell migration ISO
Inferred from Sequence Orthology
more info
 
involved_in cell migration involved in sprouting angiogenesis IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cell migration involved in sprouting angiogenesis ISO
Inferred from Sequence Orthology
more info
 
involved_in cell projection organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cell-cell adhesion mediated by integrin IEA
Inferred from Electronic Annotation
more info
 
involved_in cell-cell adhesion mediated by integrin ISO
Inferred from Sequence Orthology
more info
 
involved_in cell-matrix adhesion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within cell-matrix adhesion ISO
Inferred from Sequence Orthology
more info
 
involved_in cell-matrix adhesion ISO
Inferred from Sequence Orthology
more info
 
involved_in cell-substrate adhesion ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular response to ionizing radiation IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in cellular response to low-density lipoprotein particle stimulus IEA
Inferred from Electronic Annotation
more info
 
involved_in cellular response to low-density lipoprotein particle stimulus ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular response to low-density lipoprotein particle stimulus ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in cellular response to mechanical stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in cellular response to vitamin D IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in dendrite morphogenesis IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within dendrite morphogenesis ISO
Inferred from Sequence Orthology
more info
 
involved_in establishment of Sertoli cell barrier IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in establishment of mitotic spindle orientation IEA
Inferred from Electronic Annotation
more info
 
involved_in establishment of mitotic spindle orientation ISO
Inferred from Sequence Orthology
more info
 
involved_in formation of radial glial scaffolds IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within formation of radial glial scaffolds ISO
Inferred from Sequence Orthology
more info
 
involved_in germ cell migration IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within germ cell migration ISO
Inferred from Sequence Orthology
more info
 
involved_in heterotypic cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 
involved_in heterotypic cell-cell adhesion ISO
Inferred from Sequence Orthology
more info
 
involved_in in utero embryonic development IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within in utero embryonic development ISO
Inferred from Sequence Orthology
more info
 
involved_in integrin-mediated signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in integrin-mediated signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in integrin-mediated signaling pathway ISO
Inferred from Sequence Orthology
more info
 
involved_in lamellipodium assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in leukocyte cell-cell adhesion ISO
Inferred from Sequence Orthology
more info
 
involved_in leukocyte tethering or rolling IEA
Inferred from Electronic Annotation
more info
 
involved_in leukocyte tethering or rolling ISO
Inferred from Sequence Orthology
more info
 
involved_in maternal process involved in female pregnancy IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in mesodermal cell differentiation IEA
Inferred from Electronic Annotation
more info
 
involved_in mesodermal cell differentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in modulation of chemical synaptic transmission ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of Rho protein signal transduction IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within negative regulation of Rho protein signal transduction ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of anoikis IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of anoikis ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of apoptotic process IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of cell differentiation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within negative regulation of cell differentiation ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of cell population proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of cell projection organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of neuron differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within neuron projection development ISO
Inferred from Sequence Orthology
more info
 
involved_in phagocytosis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of GTPase activity ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of angiogenesis IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of angiogenesis ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within positive regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of cell migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within positive regulation of cell population proliferation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of cell-substrate adhesion IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of endocytosis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of fibroblast migration IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of fibroblast migration ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of glutamate uptake involved in transmission of nerve impulse IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within positive regulation of glutamate uptake involved in transmission of nerve impulse ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of neuron differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of neuron projection development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of peptidyl-tyrosine phosphorylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of protein kinase B signaling IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of protein kinase B signaling ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of protein localization to plasma membrane IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of protein localization to plasma membrane ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of protein localization to plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of signaling receptor activity ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of wound healing IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of wound healing ISO
Inferred from Sequence Orthology
more info
 
involved_in protein transport within lipid bilayer IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in reactive gliosis IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within_negative_effect reactive gliosis ISO
Inferred from Sequence Orthology
more info
 
involved_in receptor internalization IEA
Inferred from Electronic Annotation
more info
 
involved_in receptor internalization ISO
Inferred from Sequence Orthology
more info
 
involved_in receptor internalization ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in regulation of G protein-coupled receptor signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of cell cycle IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within regulation of cell cycle ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of collagen catabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of collagen catabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of collagen catabolic process ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in regulation of inward rectifier potassium channel activity IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within regulation of inward rectifier potassium channel activity ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of spontaneous synaptic transmission IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within_negative_effect regulation of spontaneous synaptic transmission ISO
Inferred from Sequence Orthology
more info
 
involved_in response to activity IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to gonadotropin IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to nutrient levels IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to transforming growth factor beta IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to xenobiotic stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in sarcomere organization IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within sarcomere organization ISO
Inferred from Sequence Orthology
more info
 
NOT involved_in stress fiber assembly ISO
Inferred from Sequence Orthology
more info
 
involved_in synaptic membrane adhesion to extracellular matrix IC
Inferred by Curator
more info
 
involved_in tissue homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
NOT involved_in transforming growth factor beta receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
involved_in visual learning IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within visual learning ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in Schaffer collateral - CA1 synapse IEA
Inferred from Electronic Annotation
more info
 
located_in Schaffer collateral - CA1 synapse ISO
Inferred from Sequence Orthology
more info
 
located_in acrosomal vesicle IDA
Inferred from Direct Assay
more info
PubMed 
located_in adherens junction IDA
Inferred from Direct Assay
more info
PubMed 
located_in basement membrane IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in cell surface IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cell surface IDA
Inferred from Direct Assay
more info
PubMed 
located_in cell surface ISO
Inferred from Sequence Orthology
more info
 
located_in cell-cell junction IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
colocalizes_with cytoplasmic vesicle ISO
Inferred from Sequence Orthology
more info
 
located_in dendritic spine IDA
Inferred from Direct Assay
more info
PubMed 
located_in dendritic spine IEA
Inferred from Electronic Annotation
more info
 
located_in dendritic spine ISO
Inferred from Sequence Orthology
more info
 
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in external side of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in filopodium IEA
Inferred from Electronic Annotation
more info
 
located_in filopodium ISO
Inferred from Sequence Orthology
more info
 
is_active_in focal adhesion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in focal adhesion IDA
Inferred from Direct Assay
more info
PubMed 
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
 
colocalizes_with focal adhesion ISO
Inferred from Sequence Orthology
more info
 
located_in focal adhesion ISO
Inferred from Sequence Orthology
more info
 
located_in glial cell projection IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in glutamatergic synapse IDA
Inferred from Direct Assay
more info
PubMed 
located_in glutamatergic synapse IDA
Inferred from Direct Assay
more info
PubMed 
located_in glutamatergic synapse IEA
Inferred from Electronic Annotation
more info
 
located_in glutamatergic synapse ISO
Inferred from Sequence Orthology
more info
 
located_in hemidesmosome IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in integral component of postsynaptic membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in integral component of postsynaptic membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in integral component of synaptic membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in integral component of synaptic membrane ISO
Inferred from Sequence Orthology
more info
 
part_of integrin alpha1-beta1 complex IEA
Inferred from Electronic Annotation
more info
 
part_of integrin alpha1-beta1 complex ISO
Inferred from Sequence Orthology
more info
 
part_of integrin alpha10-beta1 complex IEA
Inferred from Electronic Annotation
more info
 
part_of integrin alpha10-beta1 complex ISO
Inferred from Sequence Orthology
more info
 
part_of integrin alpha11-beta1 complex IEA
Inferred from Electronic Annotation
more info
 
part_of integrin alpha11-beta1 complex ISO
Inferred from Sequence Orthology
more info
 
part_of integrin alpha2-beta1 complex IEA
Inferred from Electronic Annotation
more info
 
part_of integrin alpha2-beta1 complex ISO
Inferred from Sequence Orthology
more info
 
part_of integrin alpha3-beta1 complex IDA
Inferred from Direct Assay
more info
PubMed 
part_of integrin alpha3-beta1 complex IEA
Inferred from Electronic Annotation
more info
 
part_of integrin alpha3-beta1 complex ISO
Inferred from Sequence Orthology
more info
 
part_of integrin alpha5-beta1 complex IEA
Inferred from Electronic Annotation
more info
 
part_of integrin alpha5-beta1 complex ISO
Inferred from Sequence Orthology
more info
 
part_of integrin alpha7-beta1 complex IEA
Inferred from Electronic Annotation
more info
 
part_of integrin alpha7-beta1 complex ISO
Inferred from Sequence Orthology
more info
 
part_of integrin alpha9-beta1 complex IDA
Inferred from Direct Assay
more info
PubMed 
part_of integrin complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of integrin complex IDA
Inferred from Direct Assay
more info
PubMed 
located_in intercalated disc IEA
Inferred from Electronic Annotation
more info
 
located_in intercalated disc ISO
Inferred from Sequence Orthology
more info
 
located_in lamellipodium IEA
Inferred from Electronic Annotation
more info
 
located_in melanosome IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane ISO
Inferred from Sequence Orthology
more info
 
located_in membrane raft IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane raft IEA
Inferred from Electronic Annotation
more info
 
located_in membrane raft ISO
Inferred from Sequence Orthology
more info
 
located_in myelin sheath abaxonal region IEA
Inferred from Electronic Annotation
more info
 
located_in myelin sheath abaxonal region ISO
Inferred from Sequence Orthology
more info
 
located_in neuromuscular junction IEA
Inferred from Electronic Annotation
more info
 
located_in neuromuscular junction ISO
Inferred from Sequence Orthology
more info
 
located_in perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
 
colocalizes_with perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
 
colocalizes_with plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane TAS
Traceable Author Statement
more info
 
located_in postsynaptic membrane IDA
Inferred from Direct Assay
more info
PubMed 
part_of receptor complex ISO
Inferred from Sequence Orthology
more info
 
located_in recycling endosome IEA
Inferred from Electronic Annotation
more info
 
located_in ruffle membrane IEA
Inferred from Electronic Annotation
more info
 
colocalizes_with ruffle membrane ISO
Inferred from Sequence Orthology
more info
 
located_in sarcolemma IEA
Inferred from Electronic Annotation
more info
 
located_in sarcolemma ISO
Inferred from Sequence Orthology
more info
 
located_in synapse ISO
Inferred from Sequence Orthology
more info
 
located_in synaptic membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
integrin beta-1
Names
VLA-4 subunit beta
beta OL
beta oligodendroglia
collagen alpha-1(I) chain-like
fibronectin receptor subunit beta
integrin VLA-4 subunit beta
integrin beta 1 (fibronectin receptor beta)

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_017022.2NP_058718.2  integrin beta-1 precursor

    See identical proteins and their annotated locations for NP_058718.2

    Status: VALIDATED

    Source sequence(s)
    BC131845
    UniProtKB/Swiss-Prot
    P49134
    UniProtKB/TrEMBL
    A0A0G2JSK5
    Related
    ENSRNOP00000093150.1, ENSRNOT00000109602.1
    Conserved Domains (5) summary
    smart00187
    Location:34464
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    pfam07965
    Location:640727
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:755795
    Integrin_b_cyt; Integrin beta cytoplasmic domain
    pfam18372
    Location:466495
    I-EGF_1; Integrin beta epidermal growth factor like domain 1
    NF033759
    Location:460650
    exchanger_TraA; outer membrane exchange protein TraA

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051354.1 Reference mRatBN7.2 Primary Assembly

    Range
    56705123..56753199
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006255824.2XP_006255886.1  integrin beta-1 isoform X1

    Related
    ENSRNOP00000014785.6, ENSRNOT00000014785.6
    Conserved Domains (5) summary
    smart00187
    Location:34464
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    pfam07965
    Location:640727
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:755795
    Integrin_b_cyt; Integrin beta cytoplasmic domain
    pfam18372
    Location:466495
    I-EGF_1; Integrin beta epidermal growth factor like domain 1
    NF033759
    Location:460650
    exchanger_TraA; outer membrane exchange protein TraA
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