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Il1b interleukin 1 beta [ Rattus norvegicus (Norway rat) ]

Gene ID: 24494, updated on 28-Oct-2021

Summary

Official Symbol
Il1bprovided by RGD
Official Full Name
interleukin 1 betaprovided by RGD
Primary source
RGD:2891
See related
EnsemblRapid:ENSRNOG00000004649
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
IL-1F2
Summary
an inflammatory cytokine [RGD, Feb 2006]
Expression
Biased expression in Spleen (RPKM 194.1), Lung (RPKM 63.3) and 6 other tissues See more
Orthologs
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Genomic context

See Il1b in Genome Data Viewer
Location:
3q36
Exon count:
7
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (116577005..116583386, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (121876256..121882637, complement)

Chromosome 3 - NC_051338.1Genomic Context describing neighboring genes Neighboring gene interleukin 1 alpha Neighboring gene uncharacterized LOC120101660 Neighboring gene signal-regulatory protein beta 3 Neighboring gene uncharacterized LOC102546597

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables cytokine activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables cytokine activity IDA
Inferred from Direct Assay
more info
PubMed 
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
 
enables cytokine activity ISO
Inferred from Sequence Orthology
more info
 
enables integrin binding IEA
Inferred from Electronic Annotation
more info
 
enables integrin binding ISO
Inferred from Sequence Orthology
more info
 
enables integrin binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables interleukin-1 receptor binding IEA
Inferred from Electronic Annotation
more info
 
enables protein domain specific binding IEA
Inferred from Electronic Annotation
more info
 
enables protein domain specific binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in MAPK cascade IEA
Inferred from Electronic Annotation
more info
 
involved_in MAPK cascade ISO
Inferred from Sequence Orthology
more info
 
involved_in acute inflammatory response IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in astrocyte activation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within astrocyte activation ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular response to antibiotic IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in cellular response to fatty acid IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in cellular response to glucose stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in cellular response to lipid IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in cellular response to lipopolysaccharide IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cellular response to lipopolysaccharide IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in cellular response to mechanical stimulus IEA
Inferred from Electronic Annotation
more info
 
involved_in cellular response to mechanical stimulus ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular response to organic cyclic compound IEA
Inferred from Electronic Annotation
more info
 
involved_in cellular response to organic cyclic compound ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within cellular response to organic substance ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular response to xenobiotic stimulus IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cellular response to xenobiotic stimulus ISO
Inferred from Sequence Orthology
more info
 
involved_in chronic inflammatory response to antigenic stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in cytokine-mediated signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cytokine-mediated signaling pathway ISO
Inferred from Sequence Orthology
more info
 
involved_in ectopic germ cell programmed cell death IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within ectopic germ cell programmed cell death ISO
Inferred from Sequence Orthology
more info
 
involved_in extrinsic apoptotic signaling pathway in absence of ligand IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within extrinsic apoptotic signaling pathway in absence of ligand ISO
Inferred from Sequence Orthology
more info
 
involved_in fever generation IEA
Inferred from Electronic Annotation
more info
 
involved_in fever generation IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in hyaluronan biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in hyaluronan biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 
involved_in inflammatory response IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in inflammatory response ISO
Inferred from Sequence Orthology
more info
 
involved_in interleukin-1-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in interleukin-1-mediated signaling pathway ISO
Inferred from Sequence Orthology
more info
 
involved_in learning or memory IEP
Inferred from Expression Pattern
more info
PubMed 
acts_upstream_of_or_within leukocyte migration ISO
Inferred from Sequence Orthology
more info
 
involved_in lipopolysaccharide-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in lipopolysaccharide-mediated signaling pathway ISO
Inferred from Sequence Orthology
more info
 
involved_in memory IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in monocyte aggregation IEA
Inferred from Electronic Annotation
more info
 
involved_in monocyte aggregation ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of MAP kinase activity IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of MAP kinase activity ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of adiponectin secretion IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of adiponectin secretion ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of branching morphogenesis of a nerve IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of cell population proliferation ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of extrinsic apoptotic signaling pathway in absence of ligand IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of extrinsic apoptotic signaling pathway in absence of ligand ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of gap junction assembly IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of gap junction assembly ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of gene expression IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of glucose transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of glucose transmembrane transport ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of glutamate secretion IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of insulin receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of insulin receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of lipid catabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of lipid catabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of lipid metabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of neural precursor cell proliferation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of neurogenesis IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of neuron differentiation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in negative regulation of synaptic transmission IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of synaptic transmission ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
PubMed 
involved_in neutrophil chemotaxis IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within neutrophil chemotaxis ISO
Inferred from Sequence Orthology
more info
 
involved_in ovulation IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in positive regulation of DNA-binding transcription factor activity ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of ERK1 and ERK2 cascade IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of I-kappaB kinase/NF-kappaB signaling IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of I-kappaB kinase/NF-kappaB signaling IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within positive regulation of I-kappaB kinase/NF-kappaB signaling ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of JNK cascade IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of JNK cascade IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within positive regulation of JNK cascade ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of JNK cascade ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of JUN kinase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of MAP kinase activity IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of positive regulation of MAP kinase activity ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of NF-kappaB transcription factor activity IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of positive regulation of NF-kappaB transcription factor activity ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of NF-kappaB transcription factor activity ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of NIK/NF-kappaB signaling IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of NIK/NF-kappaB signaling ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of RNA biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of T cell proliferation IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of T cell proliferation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of T-helper 1 cell cytokine production IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of T-helper 1 cell cytokine production ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of T-helper 1 cell cytokine production ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of angiogenesis IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of angiogenesis ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of astrocyte differentiation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of calcidiol 1-monooxygenase activity IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of calcidiol 1-monooxygenase activity ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of cell death IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of cell division IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of cell migration ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of cell population proliferation ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within positive regulation of chemokine production ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of complement activation IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of complement activation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of cytosolic calcium ion concentration IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of epithelial to mesenchymal transition IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of epithelial to mesenchymal transition ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of fever generation IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of fever generation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of gene expression IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in positive regulation of gene expression IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of positive regulation of gene expression ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within positive regulation of gene expression ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of gene expression ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of glial cell differentiation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of glial cell proliferation IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of glial cell proliferation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of granulocyte macrophage colony-stimulating factor production IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of granulocyte macrophage colony-stimulating factor production ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of heterotypic cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of heterotypic cell-cell adhesion ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of immature T cell proliferation in thymus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in positive regulation of immature T cell proliferation in thymus IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of inflammatory response ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of interferon-gamma production IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of interferon-gamma production ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of interferon-gamma production ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of interleukin-2 production IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of interleukin-2 production ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of interleukin-6 production IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of interleukin-6 production IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within positive regulation of interleukin-6 production ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of interleukin-6 production ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of interleukin-8 production IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of interleukin-8 production ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of lipid catabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of lipid catabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of membrane protein ectodomain proteolysis IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of membrane protein ectodomain proteolysis ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of mitotic nuclear division IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of mitotic nuclear division ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of monocyte chemotactic protein-1 production IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of monocyte chemotactic protein-1 production ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of myosin light chain kinase activity IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of myosin light chain kinase activity ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of neuron apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of neutrophil chemotaxis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of nitric oxide biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of nitric oxide biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of p38MAPK cascade IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of p38MAPK cascade ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of phagocytosis IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of phagocytosis ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of prostaglandin biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of prostaglandin biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of prostaglandin secretion IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of prostaglandin secretion ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of protein phosphorylation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of stress-activated MAPK cascade IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of stress-activated MAPK cascade IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of vascular endothelial growth factor production IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of vascular endothelial growth factor production ISO
Inferred from Sequence Orthology
more info
 
involved_in protein kinase B signaling IEA
Inferred from Electronic Annotation
more info
 
involved_in protein kinase B signaling ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of ERK1 and ERK2 cascade IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of ERK1 and ERK2 cascade ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of I-kappaB kinase/NF-kappaB signaling ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of defense response to virus by host IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of defense response to virus by host ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of establishment of endothelial barrier IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of establishment of endothelial barrier ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of insulin secretion IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of insulin secretion ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of neurogenesis IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in regulation of nitric-oxide synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of nitric-oxide synthase activity IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of nitric-oxide synthase activity ISO
Inferred from Sequence Orthology
more info
 
involved_in response to ATP IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within response to ATP ISO
Inferred from Sequence Orthology
more info
 
involved_in response to L-ascorbic acid IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to carbohydrate IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within response to carbohydrate ISO
Inferred from Sequence Orthology
more info
 
involved_in response to dexamethasone IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to estradiol IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to ethanol IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to gamma radiation IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to glucocorticoid IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to heat IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to hypoxia IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to immobilization stress IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to interleukin-1 ISO
Inferred from Sequence Orthology
more info
 
involved_in response to lipopolysaccharide IEP
Inferred from Expression Pattern
more info
PubMed 
acts_upstream_of_or_within response to lipopolysaccharide ISO
Inferred from Sequence Orthology
more info
 
involved_in response to lipopolysaccharide ISO
Inferred from Sequence Orthology
more info
 
involved_in response to morphine IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to nutrient IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to organic cyclic compound IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to organonitrogen compound IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to ozone IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to peptide hormone IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to stilbenoid IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to vitamin D IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to xenobiotic stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in sequestering of triglyceride IEA
Inferred from Electronic Annotation
more info
 
involved_in sequestering of triglyceride ISO
Inferred from Sequence Orthology
more info
 
involved_in social behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in vascular endothelial growth factor production IEA
Inferred from Electronic Annotation
more info
 
involved_in vascular endothelial growth factor production ISO
Inferred from Sequence Orthology
more info
 
involved_in vascular endothelial growth factor production ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in wound healing IEP
Inferred from Expression Pattern
more info
PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 
located_in extracellular region ISO
Inferred from Sequence Orthology
more info
 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in extracellular space IDA
Inferred from Direct Assay
more info
PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 
located_in extracellular space ISO
Inferred from Sequence Orthology
more info
 
located_in lysosome IEA
Inferred from Electronic Annotation
more info
 
located_in secretory granule IEA
Inferred from Electronic Annotation
more info
 
located_in secretory granule ISO
Inferred from Sequence Orthology
more info
 
located_in vesicle ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
interleukin-1 beta
Names
IL-1 beta

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_031512.2NP_113700.2  interleukin-1 beta

    See identical proteins and their annotated locations for NP_113700.2

    Status: PROVISIONAL

    Source sequence(s)
    BC091141
    UniProtKB/TrEMBL
    Q5BKB0
    Related
    ENSRNOP00000006308.2, ENSRNOT00000006308.5
    Conserved Domains (2) summary
    smart00125
    Location:119264
    IL1; Interleukin-1 homologues
    pfam02394
    Location:1101
    IL1_propep; Interleukin-1 propeptide

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051338.1 Reference mRatBN7.2 Primary Assembly

    Range
    116577005..116583386 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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