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Dpy19l1 dpy-19 like C-mannosyltransferase 1 [ Mus musculus (house mouse) ]

Gene ID: 244745, updated on 4-May-2024

Summary

Official Symbol
Dpy19l1provided by MGI
Official Full Name
dpy-19 like C-mannosyltransferase 1provided by MGI
Primary source
MGI:MGI:1915685
See related
Ensembl:ENSMUSG00000043067 AllianceGenome:MGI:1915685
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
6030402K12; 1100001I19Rik
Summary
Predicted to enable mannosyltransferase activity. Predicted to be involved in protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in nuclear inner membrane. Is expressed in brain; lung; metanephros; and sensory organ. Orthologous to human DPY19L1 (dpy-19 like C-mannosyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E14 (RPKM 16.6), cortex adult (RPKM 15.2) and 28 other tissues See more
Orthologs
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Genomic context

See Dpy19l1 in Genome Data Viewer
Location:
9 A4; 9 10.15 cM
Exon count:
23
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (24323074..24414436, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (24411778..24503140, complement)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_23579 Neighboring gene neuropeptide S receptor 1 Neighboring gene STARR-seq mESC enhancer starr_23580 Neighboring gene STARR-seq mESC enhancer starr_23583 Neighboring gene predicted gene 10701 Neighboring gene predicted gene, 22380 Neighboring gene predicted gene, 57533 Neighboring gene STARR-seq mESC enhancer starr_23585 Neighboring gene dpy-19 like 2 Neighboring gene STARR-seq mESC enhancer starr_23586 Neighboring gene cysteine-rich perinuclear theca 4 Neighboring gene STARR-seq mESC enhancer starr_23587 Neighboring gene STARR-seq mESC enhancer starr_23588 Neighboring gene T-box 20

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables mannosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in nuclear inner membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
protein C-mannosyl-transferase DPY19L1
Names
dpy-19-like 1
dpy-19-like protein 1
probable C-mannosyltransferase DPY19L1
protein dpy-19 homolog 1
NP_001346877.1
NP_766508.3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001359948.1NP_001346877.1  protein C-mannosyl-transferase DPY19L1

    Status: VALIDATED

    Source sequence(s)
    AC102554, BU757480, CT010514
    Consensus CDS
    CCDS22931.2
    UniProtKB/Swiss-Prot
    A6X919, Q3UP31, Q8CD79
    Related
    ENSMUSP00000119986.2, ENSMUST00000142064.8
    Conserved Domains (2) summary
    pfam10034
    Location:105742
    Dpy19; Q-cell neuroblast polarisation
    cl28033
    Location:1191
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
  2. NM_172920.4NP_766508.3  protein C-mannosyl-transferase DPY19L1

    See identical proteins and their annotated locations for NP_766508.3

    Status: VALIDATED

    Source sequence(s)
    AK143845, BU757480, CD352443, CT010514
    Consensus CDS
    CCDS22931.2
    UniProtKB/Swiss-Prot
    A6X919, Q3UP31, Q8CD79
    Related
    ENSMUSP00000129575.2, ENSMUST00000170356.2
    Conserved Domains (2) summary
    pfam10034
    Location:105742
    Dpy19; Q-cell neuroblast polarisation
    cl28033
    Location:1191
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    24323074..24414436 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)