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Zfp846 zinc finger protein 846 [ Mus musculus (house mouse) ]

Gene ID: 244721, updated on 8-Dec-2022

Summary

Official Symbol
Zfp846provided by MGI
Official Full Name
zinc finger protein 846provided by MGI
Primary source
MGI:MGI:1924012
See related
Ensembl:ENSMUSG00000058192 AllianceGenome:MGI:1924012
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Znf846; 9130221F13; 2210010B09Rik
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in bladder; female associated reproductive structure; ovary; ureter; and urethra of female. Orthologous to human ZNF699 (zinc finger protein 699). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E18 (RPKM 2.7), CNS E14 (RPKM 2.2) and 20 other tissues See more
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Genomic context

See Zfp846 in Genome Data Viewer
Location:
9; 9 A3
Exon count:
8
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (20492595..20516706)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (20581299..20605404)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 266 Neighboring gene predicted gene, 46142 Neighboring gene predicted gene, 51704 Neighboring gene F-box and leucine-rich repeat protein 12, opposite strand Neighboring gene F-box and leucine-rich repeat protein 12 Neighboring gene ubiquitin-like 5

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_172919.2NP_766507.2  zinc finger protein 846

    See identical proteins and their annotated locations for NP_766507.2

    Status: VALIDATED

    Source sequence(s)
    AK033687, BB744614, BY251235, BY726782
    Consensus CDS
    CCDS22878.2
    UniProtKB/TrEMBL
    G3X996, Q8BIQ2
    Related
    ENSMUSP00000111219.3, ENSMUST00000115557.10
    Conserved Domains (6) summary
    smart00349
    Location:1470
    KRAB; krueppel associated box
    COG5048
    Location:160528
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:164184
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:162184
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:1452
    KRAB; KRAB box
    pfam13465
    Location:176201
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    20492595..20516706
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030244362.2XP_030100222.1  zinc finger protein 846 isoform X1

    UniProtKB/TrEMBL
    Q8BIQ2
    Conserved Domains (2) summary
    COG5048
    Location:80448
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:84104
    ZF_C2H2; C2H2 Zn finger [structural motif]

RNA

  1. XR_003947898.2 RNA Sequence