4933405O20Rik RIKEN cDNA 4933405O20 gene [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: 4933405O20Rikprovided by MGI
Official Full Name: RIKEN cDNA 4933405O20 geneprovided by MGI
Primary source: MGI:MGI:2142174
See related: Ensembl:ENSMUSG00000084234 AllianceGenome:MGI:2142174
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary: Predicted to enable ATP binding activity; isocitrate dehydrogenase (NAD+) activity; and metal ion binding activity. Predicted to be involved in isocitrate metabolic process and tricarboxylic acid cycle. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human all
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Genomic context

Location:: 7; 7 B4

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
109	current	GRCm39 (GCF_000001635.27)	7	NC_000073.7 (50248938..50250276)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	7	NC_000073.6 (50599190..50600528)

Chromosome 7 - NC_000073.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Homology

Orthologs from Annotation Pipeline: 2 organisms have orthologs with human gene 4933405O20Rik
Orthologs

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in isocitrate metabolic process	IBA Inferred from Biological aspect of Ancestor more info	PubMed
involved_in tricarboxylic acid cycle	IBA Inferred from Biological aspect of Ancestor more info	PubMed

Component	Evidence Code	Pubs
located_in mitochondrion	HDA more info	PubMed
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info	PubMed

General protein information

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Preferred Names: probable isocitrate dehydrogenase [NAD] gamma 2, mitochondrial

Names: NAD(+)-specific ICDH subunit gamma 2; isocitric dehydrogenase subunit gamma 2

NP_766489.1

EC 1.1.1.41

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_172901.2 → NP_766489.1 probable isocitrate dehydrogenase [NAD] gamma 2, mitochondrial

See identical proteins and their annotated locations for NP_766489.1

Status: PROVISIONAL

Source sequence(s)

AK077105

Consensus CDS

CCDS71974.1

UniProtKB/Swiss-Prot

Q8BPC6

Related

ENSMUSP00000138215.2, ENSMUST00000119710.3

Conserved Domains (1) summary

cl00445
Location:49 → 380

Iso_dh; Isocitrate/isopropylmalate dehydrogenase