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H1f10 H1.10 linker histone [ Mus musculus (house mouse) ]

Gene ID: 243529, updated on 26-Sep-2022

Summary

Official Symbol
H1f10provided by MGI
Official Full Name
H1.10 linker histoneprovided by MGI
Primary source
MGI:MGI:2685307
See related
Ensembl:ENSMUSG00000044927 AllianceGenome:MGI:2685307
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
H1X; H1fx; Gm461; H1-10; H1.10
Summary
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H1 family. [provided by RefSeq, Nov 2015]
Orthologs
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Genomic context

See H1f10 in Genome Data Viewer
Location:
6; 6 D1
Exon count:
1
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (87957403..87958464, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (87980421..87981482, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene 5-hydroxymethylcytosine (hmC) binding, ES cell specific Neighboring gene eukaryotic translation elongation factor 1 alpha 1 pseudogene Neighboring gene ribosomal protein S19, pseudogene 9 Neighboring gene predicted gene 5577 Neighboring gene RAB7, member RAS oncogene family Neighboring gene predicted gene, 34872

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables double-stranded DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables nucleosomal DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in chromosome condensation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in negative regulation of DNA recombination IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
H1 histone family, member X

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_198622.1NP_941024.1  H1 histone family, member X

    See identical proteins and their annotated locations for NP_941024.1

    Status: REVIEWED

    Source sequence(s)
    BC048709
    Consensus CDS
    CCDS20331.1
    UniProtKB/TrEMBL
    Q80ZM5
    Related
    ENSMUSP00000060761.6, ENSMUST00000056403.7
    Conserved Domains (1) summary
    cd00073
    Location:46119
    H15; linker histone 1 and histone 5 domains; the basic subunit of chromatin is the nucleosome, consisting of an octamer of core histones, two full turns of DNA, a linker histone (H1 or H5) and a variable length of linker DNA; H1/H5 are chromatin-associated ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    87957403..87958464 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)