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Ifnlr1 interferon lambda receptor 1 [ Mus musculus (house mouse) ]

Gene ID: 242700, updated on 9-Mar-2023

Summary

Official Symbol
Ifnlr1provided by MGI
Official Full Name
interferon lambda receptor 1provided by MGI
Primary source
MGI:MGI:2429859
See related
Ensembl:ENSMUSG00000062157 AllianceGenome:MGI:2429859
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Il28ra; CRF2-12
Summary
Predicted to enable cytokine receptor activity. Involved in defense response to virus and mucosal immune response. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of interleukin-28 receptor complex. Predicted to be integral component of plasma membrane. Is expressed in alimentary system; epidermis; lower urinary tract; and sensory organ. Orthologous to human IFNLR1 (interferon lambda receptor 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in large intestine adult (RPKM 4.4), small intestine adult (RPKM 4.1) and 19 other tissues See more
Orthologs
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Genomic context

See Ifnlr1 in Genome Data Viewer
Location:
4; 4 D3
Exon count:
7
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (135413768..135435492)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (135686457..135708181)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700029M20 gene Neighboring gene predicted gene, 30941 Neighboring gene proteasome (prosome, macropain) subunit, alpha type 5 pseudogene Neighboring gene interleukin 22 receptor, alpha 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

General gene information

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables cytokine receptor activity ISO
Inferred from Sequence Orthology
more info
PubMed 
Component Evidence Code Pubs
part_of interleukin-28 receptor complex ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
interferon lambda receptor 1
Names
IFN-lambda R1
IL-28 receptor subunit alpha
IL-28R-alpha
IL-28RA
class II cytokine receptor 12
cytokine receptor class-II member 12
cytokine receptor family 2 member 12
interleukin 28 receptor alpha
interleukin-28 receptor subunit alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174851.4NP_777276.3  interferon lambda receptor 1 precursor

    See identical proteins and their annotated locations for NP_777276.3

    Status: VALIDATED

    Source sequence(s)
    AL662911
    Consensus CDS
    CCDS18788.1
    UniProtKB/Swiss-Prot
    Q6PEV1, Q8CGK5
    UniProtKB/TrEMBL
    Q3URN4
    Related
    ENSMUSP00000074009.7, ENSMUST00000074408.7
    Conserved Domains (1) summary
    pfam01108
    Location:20109
    Tissue_fac; Tissue factor

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    135413768..135435492
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)