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Tgm6 transglutaminase 6 [ Mus musculus (house mouse) ]

Gene ID: 241636, updated on 1-May-2017
Official Symbol
Tgm6provided by MGI
Official Full Name
transglutaminase 6provided by MGI
Primary source
MGI:MGI:3044321
See related
Ensembl:ENSMUSG00000027403 Vega:OTTMUSG00000015503
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
TGY; TGM3L
Orthologs
Location:
2; 2 F1
Exon count:
15
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 2 NC_000068.7 (130112416..130154232)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (129949021..129979961)

Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene transglutaminase 3, E polypeptide Neighboring gene microRNA 6339 Neighboring gene expressed sequence AU015228 Neighboring gene small nuclear ribonucleoprotein B Neighboring gene transmembrane channel-like gene family 2

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

Markers

Homology

Clone Names

  • A030011P16

Gene Ontology Provided by MGI

Function Evidence Code Pubs
protein-glutamine gamma-glutamyltransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
protein-glutamine gamma-glutamyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
protein-glutamine gamma-glutamyltransferase 6
NP_001276676.1
NP_001276677.1
NP_001276678.1
NP_808394.1
XP_017173692.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001289747.1NP_001276676.1  protein-glutamine gamma-glutamyltransferase 6 isoform 2

    See identical proteins and their annotated locations for NP_001276676.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at a downstream start codon, compared to variant 1. Variants 2, 3 and 4 encode the same isoform (2), which is shorter and has a distinct N-terminus, compared to isoform 1.
    Source sequence(s)
    AK037229, AL833804, BB612839, BC113796
    UniProtKB/TrEMBL
    Q14CG3, Q8BM11
    Conserved Domains (3) summary
    smart00460
    Location:45136
    TGc; Transglutaminase/protease-like homologues
    COG1305
    Location:47144
    YebA; Transglutaminase-like enzyme, putative cysteine protease [Posttranslational modification, protein turnover, chaperones]
    pfam00927
    Location:272377
    Transglut_C; Transglutaminase family, C-terminal ig like domain
  2. NM_001289748.1NP_001276677.1  protein-glutamine gamma-glutamyltransferase 6 isoform 2

    See identical proteins and their annotated locations for NP_001276677.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at a downstream start codon, compared to variant 1. Variants 2, 3 and 4 encode the same isoform (2), which is shorter and has a distinct N-terminus, compared to isoform 1.
    Source sequence(s)
    AK037229, AL833804, BC113796
    UniProtKB/TrEMBL
    Q14CG3, Q8BM11
    Conserved Domains (3) summary
    smart00460
    Location:45136
    TGc; Transglutaminase/protease-like homologues
    COG1305
    Location:47144
    YebA; Transglutaminase-like enzyme, putative cysteine protease [Posttranslational modification, protein turnover, chaperones]
    pfam00927
    Location:272377
    Transglut_C; Transglutaminase family, C-terminal ig like domain
  3. NM_001289749.1NP_001276678.1  protein-glutamine gamma-glutamyltransferase 6 isoform 2

    See identical proteins and their annotated locations for NP_001276678.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at a downstream start codon, compared to variant 1. Variants 2, 3 and 4 encode the same isoform (2), which is shorter and has a distinct N-terminus, compared to isoform 1.
    Source sequence(s)
    AK037229, AL833804, BB612839, BC113796
    UniProtKB/TrEMBL
    Q14CG3, Q8BM11
    Conserved Domains (3) summary
    smart00460
    Location:45136
    TGc; Transglutaminase/protease-like homologues
    COG1305
    Location:47144
    YebA; Transglutaminase-like enzyme, putative cysteine protease [Posttranslational modification, protein turnover, chaperones]
    pfam00927
    Location:272377
    Transglut_C; Transglutaminase family, C-terminal ig like domain
  4. NM_177726.4NP_808394.1  protein-glutamine gamma-glutamyltransferase 6 isoform 1

    See identical proteins and their annotated locations for NP_808394.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AK037229, AL833804, BB612839, BC113796
    Consensus CDS
    CCDS16734.1
    UniProtKB/TrEMBL
    Q14CG3, Q8BM11
    Related
    ENSMUSP00000028888.4, OTTMUSP00000016517, ENSMUST00000028888.4, OTTMUST00000036815
    Conserved Domains (4) summary
    smart00460
    Location:268359
    TGc; Transglutaminase/protease-like homologues
    COG1305
    Location:270367
    YebA; Transglutaminase-like enzyme, putative cysteine protease [Posttranslational modification, protein turnover, chaperones]
    pfam00868
    Location:5117
    Transglut_N; Transglutaminase family
    pfam00927
    Location:495600
    Transglut_C; Transglutaminase family, C-terminal ig like domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000068.7 Reference GRCm38.p4 C57BL/6J

    Range
    130112416..130154232
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017318203.1XP_017173692.1  protein-glutamine gamma-glutamyltransferase 6 isoform X1

    UniProtKB/TrEMBL
    Q14CG3
    Conserved Domains (3) summary
    smart00460
    Location:45136
    TGc; Transglutaminase/protease-like homologues
    COG1305
    Location:47144
    YebA; Transglutaminase-like enzyme, putative cysteine protease [Posttranslational modification, protein turnover, chaperones]
    pfam00927
    Location:272377
    Transglut_C; Transglutaminase family, C-terminal ig like domain
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