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Cntnap5b contactin associated protein-like 5B [ Mus musculus (house mouse) ]

Gene ID: 241175, updated on 30-Apr-2024

Summary

Official Symbol
Cntnap5bprovided by MGI
Official Full Name
contactin associated protein-like 5Bprovided by MGI
Primary source
MGI:MGI:3664583
See related
Ensembl:ENSMUSG00000067028 AllianceGenome:MGI:3664583
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Caspr5-2; C230078M14Rik
Summary
Predicted to act upstream of or within cell adhesion. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in brain and spinal cord. Orthologous to human CNTNAP5 (contactin associated protein family member 5). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis adult (RPKM 3.6), CNS E18 (RPKM 1.8) and 5 other tissues See more
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Genomic context

See Cntnap5b in Genome Data Viewer
Location:
1 E1.1; 1 48.19 cM
Exon count:
26
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (99700006..100418324)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (99772246..100490599)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 23434 Neighboring gene STARR-seq mESC enhancer starr_01796 Neighboring gene STARR-seq mESC enhancer starr_01797 Neighboring gene predicted gene, 18248 Neighboring gene predicted gene, 51641 Neighboring gene peroxiredoxin 2, pseudogene 1 Neighboring gene eukaryotic translation elongation factor 1 alpha 1 pseudogene Neighboring gene STARR-positive B cell enhancer mm9_chr1:102076636-102076937 Neighboring gene predicted gene, 53575 Neighboring gene predicted gene, 41923 Neighboring gene predicted gene, 23602 Neighboring gene predicted gene 29667 Neighboring gene baculoviral IAP repeat-containing 2 pseudogene Neighboring gene survival motor neuron 1 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

General gene information

Markers

Gene Ontology Provided by MGI

Process Evidence Code Pubs
acts_upstream_of_or_within cell adhesion IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
contactin-associated protein like 5-2
Names
cell recognition molecule Caspr5-2
cell recognition molecule Caspr5b
contactin-associated protein-like 5b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_172851.3NP_766439.2  contactin-associated protein like 5-2 precursor

    See identical proteins and their annotated locations for NP_766439.2

    Status: VALIDATED

    Source sequence(s)
    AC102217, AC135080, AC157363, AC158402, AC161355, AC163496
    Consensus CDS
    CCDS35682.1
    UniProtKB/Swiss-Prot
    Q0V8T8, Q2PAX9, Q8BUT8
    Related
    ENSMUSP00000083944.4, ENSMUST00000086738.10
    Conserved Domains (6) summary
    smart00231
    Location:56174
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain
    smart00282
    Location:205338
    LamG; Laminin G domain
    cd00057
    Location:56173
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
    cd00110
    Location:779923
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:550581
    EGF; EGF-like domain
    pfam02210
    Location:395521
    Laminin_G_2; Laminin G domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    99700006..100418324
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006529594.5XP_006529657.1  contactin-associated protein like 5-2 isoform X1

    Conserved Domains (5) summary
    smart00282
    Location:205338
    LamG; Laminin G domain
    cd00057
    Location:56173
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
    cd00110
    Location:780924
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:551582
    EGF; EGF-like domain
    pfam02210
    Location:396519
    Laminin_G_2; Laminin G domain
  2. XM_036165066.1XP_036020959.1  contactin-associated protein like 5-2 isoform X3

    Conserved Domains (3) summary
    cd00110
    Location:150294
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:318351
    EGF; EGF-like domain
    pfam02210
    Location:402530
    Laminin_G_2; Laminin G domain
  3. XM_036165065.1XP_036020958.1  contactin-associated protein like 5-2 isoform X2

    UniProtKB/TrEMBL
    B7ZP40
    Conserved Domains (3) summary
    cd00110
    Location:198342
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:366399
    EGF; EGF-like domain
    pfam02210
    Location:450578
    Laminin_G_2; Laminin G domain
  4. XM_011248005.2XP_011246307.1  contactin-associated protein like 5-2 isoform X3

    Conserved Domains (3) summary
    cd00110
    Location:150294
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:318351
    EGF; EGF-like domain
    pfam02210
    Location:402530
    Laminin_G_2; Laminin G domain