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Vax2 ventral anterior homeobox 2 [ Mus musculus (house mouse) ]

Gene ID: 24113, updated on 23-Jun-2021

Summary

Official Symbol
Vax2provided by MGI
Official Full Name
ventral anterior homeobox 2provided by MGI
Primary source
MGI:MGI:1346018
See related
Ensembl:ENSMUSG00000034777
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Dres93
Expression
Biased expression in testis adult (RPKM 1.1), limb E14.5 (RPKM 0.3) and 5 other tissues See more
Orthologs
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Genomic context

See Vax2 in Genome Data Viewer
Location:
6 C3; 6 35.94 cM
Exon count:
3
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (83688221..83715295)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (83711239..83738313)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (83661258..83688298)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene C-type lectin domain family 4, member f Neighboring gene CD207 antigen Neighboring gene ventral anterior homeobox 2, opposite strand Neighboring gene predicted gene, 32943 Neighboring gene predicted gene, 25054 Neighboring gene ATPase, H+ transporting, lysosomal V1 subunit B1 Neighboring gene RIKEN cDNA 1700124L16 gene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC144411, MGC144412

Gene Ontology Provided by MGI

Process Evidence Code Pubs
acts_upstream_of_or_within Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within axonogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within camera-type eye development IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in central nervous system development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within dorsal/ventral axis specification IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within embryonic eye morphogenesis IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within embryonic eye morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in forebrain development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in neuron differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within retina development in camera-type eye IDA
Inferred from Direct Assay
more info
PubMed 
involved_in visual perception IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
ventral anterior homeobox 2
Names
ventral anterior homeobox containing gene 2
ventral retina homeodomain protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011912.4NP_036042.1  ventral anterior homeobox 2

    See identical proteins and their annotated locations for NP_036042.1

    Status: VALIDATED

    Source sequence(s)
    AC090647
    Consensus CDS
    CCDS20282.1
    UniProtKB/Swiss-Prot
    Q9WTP9
    UniProtKB/TrEMBL
    Q14B19
    Related
    ENSMUSP00000035976.2, ENSMUST00000037807.3
    Conserved Domains (1) summary
    pfam00046
    Location:105158
    Homeobox; Homeobox domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    83688221..83715295
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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