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Tekt2 tektin 2 [ Mus musculus (house mouse) ]

Gene ID: 24084, updated on 1-Mar-2024

Summary

Official Symbol
Tekt2provided by MGI
Official Full Name
tektin 2provided by MGI
Primary source
MGI:MGI:1346335
See related
Ensembl:ENSMUSG00000028845 AllianceGenome:MGI:1346335
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
tektin-t
Summary
Acts upstream of or within flagellated sperm motility and inner dynein arm assembly. Located in microtubule organizing center. Is expressed in islets of Langerhans; pancreas; pancreas primordium; pancreas trunk epithelium; and pancreatic duct. Orthologous to human TEKT2 (tektin 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis adult (RPKM 147.5) and limb E14.5 (RPKM 8.4) See more
Orthologs
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Genomic context

See Tekt2 in Genome Data Viewer
Location:
4 D2.2; 4 60.37 cM
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (126215914..126219481, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (126322121..126325688, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene collagen, type VIII, alpha 2 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:125998967-125999150 Neighboring gene ADP-ribosylserine hydrolase Neighboring gene STARR-seq mESC enhancer starr_11400 Neighboring gene argonaute RISC catalytic subunit 3 Neighboring gene STARR-seq mESC enhancer starr_11401 Neighboring gene STARR-positive B cell enhancer ABC_E7988 Neighboring gene argonaute RISC catalytic subunit 1 Neighboring gene STARR-seq mESC enhancer starr_11403 Neighboring gene STARR-positive B cell enhancer ABC_E2714

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Process Evidence Code Pubs
acts_upstream_of_or_within cell projection organization IEA
Inferred from Electronic Annotation
more info
 
involved_in cilium assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in cilium movement involved in cell motility IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in cilium movement involved in cell motility IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within flagellated sperm motility IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within inner dynein arm assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in axonemal A tubule inner sheath IDA
Inferred from Direct Assay
more info
PubMed 
located_in axonemal microtubule ISO
Inferred from Sequence Orthology
more info
 
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
located_in cilium IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
located_in microtubule IEA
Inferred from Electronic Annotation
more info
 
is_active_in microtubule cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in microtubule organizing center IDA
Inferred from Direct Assay
more info
PubMed 
located_in motile cilium IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
tektin-2
Names
testicular tektin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001357262.1NP_001344191.1  tektin-2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1-3 all encode the same protein.
    Source sequence(s)
    AK006205, AL606976, BG083070, BY084876, BY094167
    Consensus CDS
    CCDS18651.1
    UniProtKB/Swiss-Prot
    Q922G7, Q9WVR0
    Related
    ENSMUSP00000099676.2, ENSMUST00000102616.8
    Conserved Domains (1) summary
    pfam03148
    Location:17395
    Tektin; Tektin family
  2. NM_001357263.1NP_001344192.1  tektin-2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1-3 all encode the same protein.
    Source sequence(s)
    AK006205, AL606976, BB603783, BG083070, BY084876, BY094167
    Consensus CDS
    CCDS18651.1
    UniProtKB/Swiss-Prot
    Q922G7, Q9WVR0
    Conserved Domains (1) summary
    pfam03148
    Location:17395
    Tektin; Tektin family
  3. NM_011902.3NP_036032.2  tektin-2

    See identical proteins and their annotated locations for NP_036032.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) reprsents the longest transcript. Variants 1-3 all encode the same protein.
    Source sequence(s)
    AK006205, AL606976, BG083070, BY084876, BY094167
    Consensus CDS
    CCDS18651.1
    UniProtKB/Swiss-Prot
    Q922G7, Q9WVR0
    Conserved Domains (1) summary
    pfam03148
    Location:17395
    Tektin; Tektin family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    126215914..126219481 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)