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Mcmdc2 minichromosome maintenance domain containing 2 [ Mus musculus (house mouse) ]

Gene ID: 240697, updated on 8-Feb-2024

Summary

Official Symbol
Mcmdc2provided by MGI
Official Full Name
minichromosome maintenance domain containing 2provided by MGI
Primary source
MGI:MGI:3045334
See related
Ensembl:ENSMUSG00000046101 AllianceGenome:MGI:3045334
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
6030422M02Rik
Summary
Predicted to enable ATP binding activity and DNA binding activity. Acts upstream of or within gamete generation and meiosis I cell cycle process. Orthologous to human MCMDC2 (minichromosome maintenance domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See Mcmdc2 in Genome Data Viewer
Location:
1 A2; 1 2.19 cM
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (9978863..10011179)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (9906157..9943606)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene predicted pseudogene 6195 Neighboring gene serum/glucocorticoid regulated kinase 3 Neighboring gene STARR-seq mESC enhancer starr_00172 Neighboring gene mitochondrial ribosomal protein S36 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E4304 Neighboring gene small nucleolar RNA, C/D box 87 Neighboring gene small nucleolar RNA host gene 6 Neighboring gene transcription factor 24

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
minichromosome maintenance domain-containing protein 2
Names
MCM domain-containing protein 2
MCM domain-containing protein C8orf45 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177722.3NP_808390.2  minichromosome maintenance domain-containing protein 2

    See identical proteins and their annotated locations for NP_808390.2

    Status: PROVISIONAL

    Source sequence(s)
    AC102570, AK031395, CA978963
    Consensus CDS
    CCDS48215.1
    UniProtKB/Swiss-Prot
    D3YTV7, D6RHP3, E9Q956, Q8CD58
    UniProtKB/TrEMBL
    H7BXC1
    Related
    ENSMUSP00000128620.2, ENSMUST00000171802.8
    Conserved Domains (2) summary
    cl28901
    Location:395621
    MCM; MCM helicase family
    pfam17855
    Location:557622
    MCM_lid; MCM AAA-lid domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    9978863..10011179
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011238376.3XP_011236678.1  minichromosome maintenance domain-containing protein 2 isoform X1

    See identical proteins and their annotated locations for XP_011236678.1

    UniProtKB/Swiss-Prot
    D3YTV7, D6RHP3, E9Q956, Q8CD58
    UniProtKB/TrEMBL
    H7BXC1
    Related
    ENSMUSP00000120858.3, ENSMUST00000125294.9
    Conserved Domains (2) summary
    cl28901
    Location:395621
    MCM; MCM helicase family
    pfam17855
    Location:557622
    MCM_lid; MCM AAA-lid domain