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Spry4 sprouty RTK signaling antagonist 4 [ Mus musculus (house mouse) ]

Gene ID: 24066, updated on 16-Oct-2021

Summary

Official Symbol
Spry4provided by MGI
Official Full Name
sprouty RTK signaling antagonist 4provided by MGI
Primary source
MGI:MGI:1345144
See related
Ensembl:ENSMUSG00000024427
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
sprouty4; A030006O18Rik
Expression
Ubiquitous expression in lung adult (RPKM 10.0), limb E14.5 (RPKM 8.2) and 28 other tissues See more
Orthologs
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Genomic context

See Spry4 in Genome Data Viewer
Location:
18 B3; 18 20.5 cM
Exon count:
3
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (38719300..38734400, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (38586247..38601347, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 18 NC_000084.5 (38745919..38760922, complement)

Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 41704 Neighboring gene proteasome (prosome, macropain) subunit, alpha type 2 pseudogene Neighboring gene Rho GTPase activating protein 26 Neighboring gene predicted gene, 19774 Neighboring gene ribosomal protein S2 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein kinase inhibitor activity ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011898.3NP_036028.2  protein sprouty homolog 4

    See identical proteins and their annotated locations for NP_036028.2

    Status: VALIDATED

    Source sequence(s)
    AC151580, AK034201, AK048122, BC050944
    Consensus CDS
    CCDS29202.1
    UniProtKB/Swiss-Prot
    Q9WTP2
    Related
    ENSMUSP00000025295.7, ENSMUST00000025295.8
    Conserved Domains (1) summary
    pfam05210
    Location:165267
    Sprouty; Sprouty protein (Spry)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000084.7 Reference GRCm39 C57BL/6J

    Range
    38719300..38734400 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036161148.1XP_036017041.1  protein sprouty homolog 4 isoform X1

    Conserved Domains (1) summary
    pfam05210
    Location:165267
    Sprouty; Sprouty protein (Spry)
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