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Spry4 sprouty RTK signaling antagonist 4 [ Mus musculus (house mouse) ]

Gene ID: 24066, updated on 19-May-2018
Official Symbol
Spry4provided by MGI
Official Full Name
sprouty RTK signaling antagonist 4provided by MGI
Primary source
MGI:MGI:1345144
See related
Ensembl:ENSMUSG00000024427
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
sprouty4; A030006O18Rik
Expression
Ubiquitous expression in lung adult (RPKM 10.0), limb E14.5 (RPKM 8.2) and 28 other tissues See more
Orthologs
See Spry4 in Genome Data Viewer
Location:
18 B3; 18 20.5 cM
Exon count:
2
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 18 NC_000084.6 (38586265..38601268, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 18 NC_000084.5 (38745919..38760922, complement)

Chromosome 18 - NC_000084.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 41704 Neighboring gene proteasome (prosome, macropain) subunit, alpha type 2 pseudogene Neighboring gene Rho GTPase activating protein 26 Neighboring gene predicted gene, 19774 Neighboring gene predicted gene, 46642 Neighboring gene ribosomal protein S2 pseudogene

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
animal organ development IBA
Inferred from Biological aspect of Ancestor
more info
 
cellular response to leukemia inhibitory factor IEP
Inferred from Expression Pattern
more info
PubMed 
multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
negative regulation of ERK1 and ERK2 cascade IEA
Inferred from Electronic Annotation
more info
 
negative regulation of MAP kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
negative regulation of MAP kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of Ras protein signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
 
negative regulation of fibroblast growth factor receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
regulation of signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
protein sprouty homolog 4
Names
sprouty homolog 4
spry-4

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011898.2NP_036028.2  protein sprouty homolog 4

    See identical proteins and their annotated locations for NP_036028.2

    Status: PROVISIONAL

    Source sequence(s)
    BC050944
    Consensus CDS
    CCDS29202.1
    UniProtKB/Swiss-Prot
    Q9WTP2
    Related
    ENSMUSP00000025295.6, ENSMUST00000025295.6
    Conserved Domains (1) summary
    pfam05210
    Location:166263
    Sprouty; Sprouty protein (Spry)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000084.6 Reference GRCm38.p4 C57BL/6J

    Range
    38586265..38601268 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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