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Dmxl1 Dmx-like 1 [ Mus musculus (house mouse) ]

Gene ID: 240283, updated on 5-Mar-2024

Summary

Official Symbol
Dmxl1provided by MGI
Official Full Name
Dmx-like 1provided by MGI
Primary source
MGI:MGI:2443926
See related
Ensembl:ENSMUSG00000037416 AllianceGenome:MGI:2443926
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
D030030C22; C630007L23Rik
Summary
Predicted to be involved in vacuolar acidification. Predicted to be part of RAVE complex. Orthologous to human DMXL1 (Dmx like 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in placenta adult (RPKM 4.7), cerebellum adult (RPKM 3.5) and 28 other tissues See more
Orthologs
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Genomic context

See Dmxl1 in Genome Data Viewer
Location:
18 D1; 18 27.12 cM
Exon count:
45
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (49965657..50098540)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (49832590..49965473)

Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700065O20 gene Neighboring gene predicted gene, 57648 Neighboring gene STARR-seq mESC enhancer starr_44570 Neighboring gene STARR-seq mESC enhancer starr_44572 Neighboring gene STARR-positive B cell enhancer ABC_E1957 Neighboring gene tumor necrosis factor, alpha-induced protein 8 Neighboring gene STARR-positive B cell enhancer ABC_E7584 Neighboring gene STARR-positive B cell enhancer ABC_E8716 Neighboring gene CapStarr-seq enhancer MGSCv37_chr18:50183799-50183908 Neighboring gene STARR-positive B cell enhancer ABC_E4248 Neighboring gene predicted gene, 33335 Neighboring gene RIKEN cDNA C030005K06 gene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in vacuolar acidification IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of RAVE complex IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
dmX-like protein 1
Names
X-like 1 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081371.2NP_001074840.2  dmX-like protein 1

    See identical proteins and their annotated locations for NP_001074840.2

    Status: VALIDATED

    Source sequence(s)
    AC113451, AC166570, AEKQ02092752
    Consensus CDS
    CCDS37816.2
    UniProtKB/Swiss-Prot
    Q3TLG8, Q6PHM6, Q6PNC0, Q8BQF2
    UniProtKB/TrEMBL
    F8WGX5
    Related
    ENSMUSP00000137871.2, ENSMUST00000180611.8
    Conserved Domains (4) summary
    COG2319
    Location:27663008
    WD40; WD40 repeat [General function prediction only]
    pfam12234
    Location:11391875
    Rav1p_C; RAVE protein 1 C terminal
    sd00039
    Location:27772822
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:27332990
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000084.7 Reference GRCm39 C57BL/6J

    Range
    49965657..50098540
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006525916.4XP_006525979.1  dmX-like protein 1 isoform X1

    UniProtKB/TrEMBL
    F8WGX5
    Conserved Domains (3) summary
    sd00039
    Location:28362881
    7WD40; WD40 repeat [structural motif]
    pfam12234
    Location:11391875
    Rav1p_C; RAVE protein 1 C terminal
    cl29593
    Location:27923049
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  2. XM_006525917.4XP_006525980.1  dmX-like protein 1 isoform X2

    UniProtKB/TrEMBL
    F8WGX5
    Conserved Domains (3) summary
    sd00039
    Location:28152860
    7WD40; WD40 repeat [structural motif]
    pfam12234
    Location:11391875
    Rav1p_C; RAVE protein 1 C terminal
    cl29593
    Location:27713028
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  3. XM_006525918.4XP_006525981.1  dmX-like protein 1 isoform X3

    UniProtKB/TrEMBL
    F8WGX5
    Conserved Domains (3) summary
    sd00039
    Location:27982843
    7WD40; WD40 repeat [structural motif]
    pfam12234
    Location:11391875
    Rav1p_C; RAVE protein 1 C terminal
    cl29593
    Location:27543011
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  4. XM_030250455.1XP_030106315.1  dmX-like protein 1 isoform X4

    UniProtKB/TrEMBL
    F8WGX5
    Conserved Domains (3) summary
    sd00039
    Location:26792724
    7WD40; WD40 repeat [structural motif]
    pfam12234
    Location:9821718
    Rav1p_C; RAVE protein 1 C terminal
    cl29593
    Location:26352892
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...