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Lamp3 lysosomal-associated membrane protein 3 [ Mus musculus (house mouse) ]

Gene ID: 239739, updated on 12-Aug-2019

Summary

Official Symbol
Lamp3provided by MGI
Official Full Name
lysosomal-associated membrane protein 3provided by MGI
Primary source
MGI:MGI:2441659
See related
Ensembl:ENSMUSG00000041247
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
LAMP; Cd208; DCLAMP; TSC403; DC-LAMP; 1200002D17Rik
Expression
Restricted expression toward lung adult (RPKM 35.6) See more
Orthologs

Genomic context

See Lamp3 in Genome Data Viewer
Location:
16; 16 A3
Exon count:
6
Annotation release Status Assembly Chr Location
108 current GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (19653381..19706365, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 16 NC_000082.5 (19653474..19706458, complement)

Chromosome 16 - NC_000082.6Genomic Context describing neighboring genes Neighboring gene olfactory receptor 170 Neighboring gene olfactory receptor 171 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from BioSystems

  • Lysosome, organism-specific biosystem (from KEGG)
    Lysosome, organism-specific biosystemLysosomes are membrane-delimited organelles in animal cells serving as the cell's main digestive compartment to which all sorts of macromolecules are delivered for degradation. They contain more than...
  • Lysosome, conserved biosystem (from KEGG)
    Lysosome, conserved biosystemLysosomes are membrane-delimited organelles in animal cells serving as the cell's main digestive compartment to which all sorts of macromolecules are delivered for degradation. They contain more than...

General gene information

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
adaptive immune response IEA
Inferred from Electronic Annotation
more info
 
establishment of protein localization to organelle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
immune system process IEA
Inferred from Electronic Annotation
more info
 
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ISO
Inferred from Sequence Orthology
more info
 
negative regulation of proteasomal protein catabolic process ISO
Inferred from Sequence Orthology
more info
 
positive regulation of gene expression ISO
Inferred from Sequence Orthology
more info
 
regulation of autophagy ISO
Inferred from Sequence Orthology
more info
 
regulation of viral life cycle ISO
Inferred from Sequence Orthology
more info
 
response to interferon-alpha ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
alveolar lamellar body membrane IDA
Inferred from Direct Assay
more info
PubMed 
alveolar lamellar body membrane ISO
Inferred from Sequence Orthology
more info
 
cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 
early endosome ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
late endosome membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
lysosomal membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
lysosomal membrane IDA
Inferred from Direct Assay
more info
PubMed 
lysosome IDA
Inferred from Direct Assay
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
 
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
vesicle ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
lysosome-associated membrane glycoprotein 3
Names
DC LAMP
DC-lysosome-associated membrane glycoprotein
LAMP-3
dendritic cells-lysosome associated membrane glycoprotein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177356.3NP_796330.2  lysosome-associated membrane glycoprotein 3 precursor

    See identical proteins and their annotated locations for NP_796330.2

    Status: VALIDATED

    Source sequence(s)
    AK028039, AK033379, BY067461, BY388271
    Consensus CDS
    CCDS37285.1
    UniProtKB/Swiss-Prot
    Q7TST5
    UniProtKB/TrEMBL
    Q8BZW9
    Related
    ENSMUSP00000080556.5, ENSMUST00000081880.6
    Conserved Domains (1) summary
    pfam01299
    Location:95411
    Lamp; Lysosome-associated membrane glycoprotein (Lamp)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p6 C57BL/6J

Genomic

  1. NC_000082.6 Reference GRCm38.p6 C57BL/6J

    Range
    19653381..19706365 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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