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Csmd3 CUB and Sushi multiple domains 3 [ Mus musculus (house mouse) ]

Gene ID: 239420, updated on 12-Aug-2019

Summary

Official Symbol
Csmd3provided by MGI
Official Full Name
CUB and Sushi multiple domains 3provided by MGI
Primary source
MGI:MGI:2386403
See related
Ensembl:ENSMUSG00000022311
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mKIAA1894; 4930500N14Rik
Expression
Biased expression in CNS E18 (RPKM 1.5), frontal lobe adult (RPKM 1.2) and 6 other tissues See more
Orthologs

Genomic context

See Csmd3 in Genome Data Viewer
Location:
15; 15 B3.3
Exon count:
72
Annotation release Status Assembly Chr Location
108 current GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (47580638..48792558, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (47412184..48623535, complement)

Chromosome 15 - NC_000081.6Genomic Context describing neighboring genes Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene eukaryotic translation initiation factor 4B pseudogene Neighboring gene WD repeat domain 12 pseudogene Neighboring gene small nucleolar RNA SNORA17 Neighboring gene autophagy-related 16-like 1 pseudogene Neighboring gene U2 spliceosomal RNA Neighboring gene predicted gene, 34336 Neighboring gene Ewing sarcoma breakpoint region 1 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
regulation of dendrite development IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
CUB and sushi domain-containing protein 3
Names
CUB and sushi multiple domains protein 3

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081391.2NP_001074860.2  CUB and sushi domain-containing protein 3

    See identical proteins and their annotated locations for NP_001074860.2

    Status: VALIDATED

    Source sequence(s)
    AC099596, AC099600, AC099711, AC101706, AC101771, AC129189, AC130669, AC137905, AC154881, AC157584, AC158907
    Consensus CDS
    CCDS49602.1
    UniProtKB/Swiss-Prot
    Q80T79
    Related
    ENSMUSP00000098235.3, ENSMUST00000100670.9
    Conserved Domains (5) summary
    cd00033
    Location:28172871
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    smart00032
    Location:26322689
    CCP; Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR)
    PHA02927
    Location:31683407
    PHA02927; secreted complement-binding protein; Provisional
    cd00041
    Location:15881695
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam00084
    Location:32333286
    Sushi; Sushi repeat (SCR repeat)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p6 C57BL/6J

Genomic

  1. NC_000081.6 Reference GRCm38.p6 C57BL/6J

    Range
    47580638..48792558 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011245610.3XP_011243912.1  CUB and sushi domain-containing protein 3 isoform X1

    Conserved Domains (5) summary
    cd00033
    Location:27912845
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    smart00032
    Location:26062663
    CCP; Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR)
    PHA02927
    Location:31423381
    PHA02927; secreted complement-binding protein; Provisional
    cd00041
    Location:15621669
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam00084
    Location:32073260
    Sushi; Sushi repeat (SCR repeat)
  2. XM_030248540.1XP_030104400.1  CUB and sushi domain-containing protein 3 isoform X5

  3. XM_006520910.4XP_006520973.1  CUB and sushi domain-containing protein 3 isoform X4

    Conserved Domains (5) summary
    cd00033
    Location:26872741
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    smart00032
    Location:25022559
    CCP; Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR)
    PHA02927
    Location:30383277
    PHA02927; secreted complement-binding protein; Provisional
    cd00041
    Location:14581565
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam00084
    Location:31033156
    Sushi; Sushi repeat (SCR repeat)
  4. XM_006520909.4XP_006520972.1  CUB and sushi domain-containing protein 3 isoform X3

    Related
    ENSMUSP00000124753.1, ENSMUST00000160658.7
    Conserved Domains (5) summary
    cd00033
    Location:27132767
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    smart00032
    Location:25282585
    CCP; Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR)
    PHA02927
    Location:30643303
    PHA02927; secreted complement-binding protein; Provisional
    cd00041
    Location:14841591
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam00084
    Location:31293182
    Sushi; Sushi repeat (SCR repeat)
  5. XM_011245611.3XP_011243913.1  CUB and sushi domain-containing protein 3 isoform X2

    UniProtKB/Swiss-Prot
    Q80T79
    Conserved Domains (5) summary
    cd00033
    Location:27472801
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    smart00032
    Location:25622619
    CCP; Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR)
    PHA02927
    Location:30983337
    PHA02927; secreted complement-binding protein; Provisional
    cd00041
    Location:15881695
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam00084
    Location:31633216
    Sushi; Sushi repeat (SCR repeat)
  6. XM_006520912.3XP_006520975.1  CUB and sushi domain-containing protein 3 isoform X6

    Conserved Domains (5) summary
    cd00033
    Location:22862340
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    smart00032
    Location:21012158
    CCP; Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR)
    PHA02927
    Location:26372876
    PHA02927; secreted complement-binding protein; Provisional
    cd00041
    Location:10571164
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam00084
    Location:27022755
    Sushi; Sushi repeat (SCR repeat)
  7. XM_030248542.1XP_030104402.1  CUB and sushi domain-containing protein 3 isoform X9

    Related
    ENSMUSP00000124195.1, ENSMUST00000161653.1
  8. XM_030248541.1XP_030104401.1  CUB and sushi domain-containing protein 3 isoform X8

  9. XM_011245613.3XP_011243915.1  CUB and sushi domain-containing protein 3 isoform X7

    Conserved Domains (5) summary
    cd00033
    Location:28172871
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    smart00032
    Location:26322689
    CCP; Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR)
    PHA02927
    Location:26272872
    PHA02927; secreted complement-binding protein; Provisional
    cd00041
    Location:15881695
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam00084
    Location:15281584
    Sushi; Sushi repeat (SCR repeat)

RNA

  1. XR_001781523.2 RNA Sequence

  2. XR_003951374.1 RNA Sequence

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