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Kctd12 potassium channel tetramerisation domain containing 12 [ Mus musculus (house mouse) ]

Gene ID: 239217, updated on 8-Jan-2023

Summary

Official Symbol
Kctd12provided by MGI
Official Full Name
potassium channel tetramerisation domain containing 12provided by MGI
Primary source
MGI:MGI:2145823
See related
Ensembl:ENSMUSG00000098557 AllianceGenome:MGI:2145823
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Pfet1; Pfetin
Summary
Predicted to enable identical protein binding activity. Acts upstream of or within regulation of G protein-coupled receptor signaling pathway. Located in postsynaptic membrane and presynaptic membrane. Part of receptor complex. Is expressed in several structures, including cochlear ganglion; eye; genitourinary system; gut; and inner ear. Orthologous to human KCTD12 (potassium channel tetramerization domain containing 12). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See Kctd12 in Genome Data Viewer
Location:
14; 14 E2.3
Exon count:
1
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (103214017..103220073, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (102976581..102982637, complement)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 41234 Neighboring gene predicted gene, 34589 Neighboring gene RIKEN cDNA 4933432I03 gene Neighboring gene microRNA 5130 Neighboring gene ribosomal protein L17, pseudogene 7 Neighboring gene predicted gene, 34643

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in postsynaptic membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in postsynaptic membrane IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in presynaptic membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in presynaptic membrane IDA
Inferred from Direct Assay
more info
PubMed 
part_of receptor complex IDA
Inferred from Direct Assay
more info
PubMed 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
BTB/POZ domain-containing protein KCTD12
Names
potassium channel tetramerization domain containing 12
predominantly fetal expressed T1 domain

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177715.4NP_808383.3  BTB/POZ domain-containing protein KCTD12

    See identical proteins and their annotated locations for NP_808383.3

    Status: VALIDATED

    Source sequence(s)
    AK087895, AK173260, BP753689, CF538046
    Consensus CDS
    CCDS70611.1
    UniProtKB/Swiss-Prot
    Q6WVG3
    UniProtKB/TrEMBL
    A0A0R4J2B2, A0A6P5R091, A0A8C6H5K6, Q69ZA6, Q8C2V2
    Related
    ENSMUSP00000139261.2, ENSMUST00000184744.2
    Conserved Domains (1) summary
    cl02518
    Location:36125
    BTB; BTB/POZ domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    103214017..103220073 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)