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Il17d interleukin 17D [ Mus musculus (house mouse) ]

Gene ID: 239114, updated on 26-Sep-2022

Summary

Official Symbol
Il17dprovided by MGI
Official Full Name
interleukin 17Dprovided by MGI
Primary source
MGI:MGI:2446510
See related
Ensembl:ENSMUSG00000050222 AllianceGenome:MGI:2446510
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
IL-17D
Summary
Predicted to enable cytokine activity and protein homodimerization activity. Predicted to be involved in inflammatory response; negative regulation of hemopoiesis; and positive regulation of cytokine production. Predicted to be located in extracellular space. Is expressed in central nervous system; ganglia; nucleus pulposus; and thymus primordium. Orthologous to human IL17D (interleukin 17D). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in ovary adult (RPKM 30.3), colon adult (RPKM 25.3) and 21 other tissues See more
Orthologs
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Genomic context

See Il17d in Genome Data Viewer
Location:
14; 14 C3
Exon count:
3
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (57762286..57780623)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (57524829..57543166)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene crystallin, lambda 1 Neighboring gene predicted gene, 29717 Neighboring gene intraflagellar transport 88 Neighboring gene RIKEN cDNA 1700039M10 gene Neighboring gene EEF1A alpha lysine methyltransferase 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Targeted (1)  1 citation
  • Endonuclease-mediated (3) 

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables cytokine activity ISO
Inferred from Sequence Orthology
more info
 
enables protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
enables receptor ligand activity ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in extracellular space ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145837.4NP_665836.2  interleukin-17D precursor

    See identical proteins and their annotated locations for NP_665836.2

    Status: VALIDATED

    Source sequence(s)
    AC154675
    Consensus CDS
    CCDS49507.1
    UniProtKB/TrEMBL
    A0A0B4J1G4, A0A6P5QUV5, Q8K4C4
    Related
    ENSMUSP00000086921.5, ENSMUST00000089494.6
    Conserved Domains (1) summary
    pfam06083
    Location:96177
    IL17; Interleukin-17

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    57762286..57780623
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)