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Ccnb1ip1 cyclin B1 interacting protein 1 [ Mus musculus (house mouse) ]

Gene ID: 239083, updated on 8-Feb-2024

Summary

Official Symbol
Ccnb1ip1provided by MGI
Official Full Name
cyclin B1 interacting protein 1provided by MGI
Primary source
MGI:MGI:2685134
See related
Ensembl:ENSMUSG00000071470 AllianceGenome:MGI:2685134
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mei4; Gm288; Hei10
Summary
Predicted to enable identical protein binding activity. Involved in chiasma assembly. Acts upstream of or within blastocyst formation and spermatid development. Located in condensed nuclear chromosome. Colocalizes with synaptonemal complex. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Orthologous to human CCNB1IP1 (cyclin B1 interacting protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 2.9) See more
Orthologs
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Genomic context

See Ccnb1ip1 in Genome Data Viewer
Location:
14 C1; 14 26.25 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (51026706..51033185, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (50789249..50795728, complement)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 11 subfamily H member 4 Neighboring gene tetratricopeptide repeat domain 5 Neighboring gene STARR-positive B cell enhancer ABC_E753 Neighboring gene ribonuclease P RNA component H1 Neighboring gene poly (ADP-ribose) polymerase family, member 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
enables ubiquitin protein ligase activity TAS
Traceable Author Statement
more info
PubMed 
enables ubiquitin-protein transferase activity TAS
Traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within blastocyst formation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within chiasma assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in chiasma assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within meiotic cell cycle IEA
Inferred from Electronic Annotation
more info
 
involved_in protein ubiquitination TAS
Traceable Author Statement
more info
PubMed 
involved_in reciprocal meiotic recombination IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in reciprocal meiotic recombination IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within spermatid development IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
 
located_in condensed nuclear chromosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
colocalizes_with synaptonemal complex IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
E3 ubiquitin-protein ligase CCNB1IP1
Names
RING-type E3 ubiquitin transferase CCNB1IP1
NP_001104589.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001111119.1NP_001104589.1  E3 ubiquitin-protein ligase CCNB1IP1

    See identical proteins and their annotated locations for NP_001104589.1

    Status: PROVISIONAL

    Source sequence(s)
    AC027184
    Consensus CDS
    CCDS49477.1
    UniProtKB/Swiss-Prot
    D3Z3K2
    Related
    ENSMUSP00000093622.4, ENSMUST00000095932.5
    Conserved Domains (2) summary
    pfam13851
    Location:115163
    GAS; Growth-arrest specific micro-tubule binding
    pfam14634
    Location:1052
    zf-RING_5; zinc-RING finger domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    51026706..51033185 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)