U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Cdhr18 cadherin related family member 18 [ Mus musculus (house mouse) ]

Gene ID: 238939, updated on 19-Nov-2025
Official Symbol
Cdhr18provided by MGI
Official Full Name
cadherin related family member 18provided by MGI
Primary source
MGI:MGI:2685127
See related
Ensembl:ENSMUSG00000084902 AllianceGenome:MGI:2685127
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm281
Summary
Predicted to enable beta-catenin binding activity and cadherin binding activity. Predicted to be involved in several processes, including calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; cell-cell adhesion mediated by cadherin; and cell-cell junction organization. Predicted to be part of catenin complex. Predicted to be active in adherens junction. Orthologous to human CDHR18P (cadherin related family member 18, pseudogene). [provided by Alliance of Genome Resources, Jul 2025]
Expression
Biased expression in lung adult (RPKM 1.0) and ovary adult (RPKM 0.1) See more
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See Cdhr18 in Genome Data Viewer
Location:
14 A1; 14 7.07 cM
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (8555242..8646046)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (13828428..13914521, complement)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene ataxin 7 Neighboring gene STARR-seq mESC enhancer starr_35986 Neighboring gene predicted gene, 53821 Neighboring gene STARR-seq mESC enhancer starr_35982 Neighboring gene STARR-seq mESC enhancer starr_35981 Neighboring gene THO complex 7 Neighboring gene predicted gene 11100 Neighboring gene STARR-seq mESC enhancer starr_35980 Neighboring gene STARR-seq mESC enhancer starr_35979 Neighboring gene STARR-seq mESC enhancer starr_35978 Neighboring gene zinc finger, AN1-type domain 5 pseudogene Neighboring gene predicted gene, 25964 Neighboring gene STARR-seq mESC enhancer starr_35976 Neighboring gene STARR-seq mESC enhancer starr_35975 Neighboring gene STARR-seq mESC enhancer starr_35974 Neighboring gene ribosomal protein L19, pseudogene 4 Neighboring gene DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 pseudogene

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Related articles in PubMed

  1. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables beta-catenin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables cadherin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in adherens junction organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in calcium-dependent cell-cell adhesion IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cell migration IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cell morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
  
involved_in cell-cell adhesion mediated by cadherin IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cell-cell junction assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in homophilic cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in adherens junction IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of catenin complex IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cellular_component ND
No biological Data available
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
uncharacterized protein LOC238939

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001393529.1 → NP_001380458.1  uncharacterized protein LOC238939 precursor

    Status: VALIDATED

    Source sequence(s)
    AC171681
    UniProtKB/TrEMBL
    D3Z1Y0
    Related
    ENSMUSP00000121887.3, ENSMUST00000144914.3
    Conserved Domains (2) summary
    cd11304
    Location:471 → 569
    Cadherin_repeat; Cadherin tandem repeat domain
    cl29226
    Location:82 → 126
    Cadherin; Cadherin domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    8555242..8646046
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011244864.1 → XP_011243166.1  uncharacterized protein LOC238939 isoform X1

    UniProtKB/TrEMBL
    D3Z1Y0
    Conserved Domains (2) summary
    cd11304
    Location:471 → 569
    Cadherin_repeat; Cadherin tandem repeat domain
    cl29226
    Location:82 → 126
    Cadherin; Cadherin domain
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.