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Gpr34 G protein-coupled receptor 34 [ Mus musculus (house mouse) ]

Gene ID: 23890, updated on 21-May-2024

Summary

Official Symbol
Gpr34provided by MGI
Official Full Name
G protein-coupled receptor 34provided by MGI
Primary source
MGI:MGI:1346334
See related
Ensembl:ENSMUSG00000040229 AllianceGenome:MGI:1346334
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Lypsr1
Summary
Predicted to enable G protein-coupled purinergic nucleotide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within signal transduction. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Is expressed in several structures, including genitourinary system; liver; skeletal muscle tissue; spleen; and tongue. Orthologous to human GPR34 (G protein-coupled receptor 34). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in frontal lobe adult (RPKM 2.0), cortex adult (RPKM 2.0) and 14 other tissues See more
Orthologs
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Genomic context

See Gpr34 in Genome Data Viewer
Location:
X A1.1; X 8.55 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (13489777..13507098)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (13622650..13640859)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene nyctalopin Neighboring gene predicted gene 14506 Neighboring gene calcium/calmodulin dependent serine protein kinase Neighboring gene predicted gene, 34836 Neighboring gene G protein-coupled receptor 82 Neighboring gene nuclear encoded tRNA glutamine 1 (anticodon TTG)

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables G protein-coupled purinergic nucleotide receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
probable G-protein coupled receptor 34
Names
G-protein-coupled receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011823.5NP_035953.3  probable G-protein coupled receptor 34

    See identical proteins and their annotated locations for NP_035953.3

    Status: VALIDATED

    Source sequence(s)
    AL671117
    Consensus CDS
    CCDS30028.1
    UniProtKB/Swiss-Prot
    Q9R1K6
    UniProtKB/TrEMBL
    Q3YL73, Q8BYI1
    Related
    ENSMUSP00000042715.4, ENSMUST00000041708.10
    Conserved Domains (1) summary
    cd15148
    Location:48331
    7tmA_GPR34-like; putative G protein-coupled receptor 34, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    13489777..13507098
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006527625.5XP_006527688.1  probable G-protein coupled receptor 34 isoform X1

    See identical proteins and their annotated locations for XP_006527688.1

    UniProtKB/Swiss-Prot
    Q9R1K6
    UniProtKB/TrEMBL
    Q3YL73, Q8BYI1
    Related
    ENSMUSP00000094236.4, ENSMUST00000096492.4
    Conserved Domains (1) summary
    cd15148
    Location:48331
    7tmA_GPR34-like; putative G protein-coupled receptor 34, member of the class A family of seven-transmembrane G protein-coupled receptors
  2. XM_036161948.1XP_036017841.1  probable G-protein coupled receptor 34 isoform X1

    UniProtKB/Swiss-Prot
    Q9R1K6
    UniProtKB/TrEMBL
    Q3YL73, Q8BYI1
    Conserved Domains (1) summary
    cd15148
    Location:48331
    7tmA_GPR34-like; putative G protein-coupled receptor 34, member of the class A family of seven-transmembrane G protein-coupled receptors
  3. XM_036161949.1XP_036017842.1  probable G-protein coupled receptor 34 isoform X1

    UniProtKB/Swiss-Prot
    Q9R1K6
    UniProtKB/TrEMBL
    Q3YL73, Q8BYI1
    Conserved Domains (1) summary
    cd15148
    Location:48331
    7tmA_GPR34-like; putative G protein-coupled receptor 34, member of the class A family of seven-transmembrane G protein-coupled receptors