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Mylk4 myosin light chain kinase family, member 4 [ Mus musculus (house mouse) ]

Gene ID: 238564, updated on 17-Aug-2019

Summary

Official Symbol
Mylk4provided by MGI
Official Full Name
myosin light chain kinase family, member 4provided by MGI
Primary source
MGI:MGI:3643758
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
EG238564
Expression
Biased expression in heart adult (RPKM 15.6), mammary gland adult (RPKM 3.8) and 1 other tissue See more
Orthologs

Genomic context

See Mylk4 in Genome Data Viewer
Location:
13; 13 A3.2
Exon count:
17
Annotation release Status Assembly Chr Location
108 current GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (32700824..32806773, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (32792696..32873648, complement)

Chromosome 13 - NC_000079.6Genomic Context describing neighboring genes Neighboring gene GDP-mannose 4, 6-dehydratase Neighboring gene predicted gene, 52055 Neighboring gene predicted gene, 40876 Neighboring gene serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene Neighboring gene serine (or cysteine) peptidase inhibitor, clade B, member 1a Neighboring gene Werner helicase interacting protein 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
myosin light chain kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
myosin light chain kinase family member 4
Names
sgK085
sugen kinase 85
NP_001355809.1
XP_006516729.1
XP_006516730.1
XP_006516731.1
XP_006516733.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001368880.1NP_001355809.1  myosin light chain kinase family member 4

    Status: VALIDATED

    Source sequence(s)
    AL645808
    Conserved Domains (1) summary
    cl21453
    Location:339599
    PKc_like; Protein Kinases, catalytic domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p6 C57BL/6J

Genomic

  1. NC_000079.6 Reference GRCm38.p6 C57BL/6J

    Range
    32700824..32806773 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006516667.3XP_006516730.1  myosin light chain kinase family member 4 isoform X2

    Conserved Domains (2) summary
    smart00220
    Location:391642
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cl21453
    Location:382642
    PKc_like; Protein Kinases, catalytic domain
  2. XM_006516670.3XP_006516733.1  myosin light chain kinase family member 4 isoform X4

    Conserved Domains (2) summary
    smart00220
    Location:342593
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cl21453
    Location:333593
    PKc_like; Protein Kinases, catalytic domain
  3. XM_006516666.3XP_006516729.1  myosin light chain kinase family member 4 isoform X1

    Conserved Domains (2) summary
    smart00220
    Location:404655
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cl21453
    Location:395655
    PKc_like; Protein Kinases, catalytic domain
  4. XM_006516668.4XP_006516731.1  myosin light chain kinase family member 4 isoform X3

    Conserved Domains (2) summary
    smart00220
    Location:380631
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14193
    Location:371631
    STKc_MLCK4; Catalytic domain of the Serine/Threonine Kinase, Myosin Light Chain Kinase 4

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001166030.1: Suppressed sequence

    Description
    NM_001166030.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
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